From Wikipedia, the free encyclopedia
Panipenem/betamipron
Combination of
Panipenem Carbapenem antibiotic
BetamipronInhibitor of renal panipenem uptake
Clinical data
Trade namesCarbenin
AHFS/ Drugs.com International Drug Names
Routes of
administration
Intravenous
ATC code
Identifiers
CAS Number
PubChem CID
KEGG

Panipenem/betamipron is a carbapenem antibiotic [1] marketed by Daiichi Sankyo Co. of Japan. It was launched in 1993, [2] under the brand name Carbenin. [3]

It is a combination in which panipenem is the carbapenem antibiotic and betamipron inhibits renal uptake of panipenem [4] and so reduces its nephrotoxicity [5] (much like the imipenem/cilastatin combination).

References

  1. ^ Hikida M, Terashima S, Sato Y, Okamoato R, Inoue M (November 2001). "[Comparative antibacterial activity of carbapenems against P. aeruginosa (1)]". The Japanese Journal of Antibiotics. 54 (11): 571–9. doi: 10.11553/antibiotics1968b.54.571. PMID  11828603.
  2. ^ "Sankyo Launch". The Pharmaletter. 1994-01-24.
  3. ^ International Drug Names: Carbenin.
  4. ^ Finch RG (2003). Antibiotic and chemotherapy: anti-infective agents and their use in therapy. Elsevier Health Sciences. pp. 269ff. ISBN  978-0-443-07129-4. Retrieved 8 August 2011.
  5. ^ Goa KL, Noble S (2003). "Panipenem/betamipron". Drugs. 63 (9): 913–25, discussion 926. doi: 10.2165/00003495-200363090-00005. PMID  12678575. S2CID  263994230.
From Wikipedia, the free encyclopedia
Panipenem/betamipron
Combination of
Panipenem Carbapenem antibiotic
BetamipronInhibitor of renal panipenem uptake
Clinical data
Trade namesCarbenin
AHFS/ Drugs.com International Drug Names
Routes of
administration
Intravenous
ATC code
Identifiers
CAS Number
PubChem CID
KEGG

Panipenem/betamipron is a carbapenem antibiotic [1] marketed by Daiichi Sankyo Co. of Japan. It was launched in 1993, [2] under the brand name Carbenin. [3]

It is a combination in which panipenem is the carbapenem antibiotic and betamipron inhibits renal uptake of panipenem [4] and so reduces its nephrotoxicity [5] (much like the imipenem/cilastatin combination).

References

  1. ^ Hikida M, Terashima S, Sato Y, Okamoato R, Inoue M (November 2001). "[Comparative antibacterial activity of carbapenems against P. aeruginosa (1)]". The Japanese Journal of Antibiotics. 54 (11): 571–9. doi: 10.11553/antibiotics1968b.54.571. PMID  11828603.
  2. ^ "Sankyo Launch". The Pharmaletter. 1994-01-24.
  3. ^ International Drug Names: Carbenin.
  4. ^ Finch RG (2003). Antibiotic and chemotherapy: anti-infective agents and their use in therapy. Elsevier Health Sciences. pp. 269ff. ISBN  978-0-443-07129-4. Retrieved 8 August 2011.
  5. ^ Goa KL, Noble S (2003). "Panipenem/betamipron". Drugs. 63 (9): 913–25, discussion 926. doi: 10.2165/00003495-200363090-00005. PMID  12678575. S2CID  263994230.

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