Combination of | |
---|---|
Benzylpenicillin | antibiotic |
Procaine | anaesthetic |
Clinical data | |
Trade names | Bicillin C-R, [1] other |
Other names | penicillin G procaine, procaine penicillin G, procaine penicillin |
AHFS/ Drugs.com | FDA Professional Drug Information |
Routes of administration | IM |
ATC code | |
Legal status | |
Legal status |
|
Identifiers | |
CAS Number | |
UNII | |
ChEMBL | |
E number | E707 (antibiotics) |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.000.187 |
(what is this?) (verify) |
Procaine benzylpenicillin also known as penicillin G procaine, is an antibiotic useful for the treatment of a number of bacterial infections. [2] Specifically it is used for syphilis, anthrax, mouth infections, pneumonia, diphtheria, cellulitis, and animal bites. [2] It is given by injection into a muscle. [2]
Side effects include pain at the site of injection, blood clotting problems, seizures, and allergic reactions including anaphylaxis. [2] When used to treat syphilis a reaction known as Jarisch-Herxheimer may occur. [2] It is not recommended in those with a history of penicillin allergy or procaine allergy. [1] [2] Use during pregnancy and breastfeeding is relatively safe. [1] [2] Procaine benzylpenicillin is in the penicillin and beta lactam family of medications. [2] It works via benzylpenicillin and results in bacterial death. [2] [3] Procaine makes the combination long acting. [4]
Procaine benzylpenicillin was introduced for medical use in 1948. [3] It is on the World Health Organization's List of Essential Medicines. [5]
Specific indications for procaine penicillin include: [6]
At high doses procaine penicillin can cause seizures and CNS abnormalities due to procaine present in it.[ citation needed]
It is a form of penicillin which is a combination of benzylpenicillin and the local anaesthetic agent procaine. [9] Following deep intramuscular injection, it is slowly absorbed into the circulation and hydrolysed to benzylpenicillin — thus it is used where prolonged low concentrations of benzylpenicillin are required.
Combination of | |
---|---|
Benzylpenicillin | antibiotic |
Procaine | anaesthetic |
Clinical data | |
Trade names | Bicillin C-R, [1] other |
Other names | penicillin G procaine, procaine penicillin G, procaine penicillin |
AHFS/ Drugs.com | FDA Professional Drug Information |
Routes of administration | IM |
ATC code | |
Legal status | |
Legal status |
|
Identifiers | |
CAS Number | |
UNII | |
ChEMBL | |
E number | E707 (antibiotics) |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.000.187 |
(what is this?) (verify) |
Procaine benzylpenicillin also known as penicillin G procaine, is an antibiotic useful for the treatment of a number of bacterial infections. [2] Specifically it is used for syphilis, anthrax, mouth infections, pneumonia, diphtheria, cellulitis, and animal bites. [2] It is given by injection into a muscle. [2]
Side effects include pain at the site of injection, blood clotting problems, seizures, and allergic reactions including anaphylaxis. [2] When used to treat syphilis a reaction known as Jarisch-Herxheimer may occur. [2] It is not recommended in those with a history of penicillin allergy or procaine allergy. [1] [2] Use during pregnancy and breastfeeding is relatively safe. [1] [2] Procaine benzylpenicillin is in the penicillin and beta lactam family of medications. [2] It works via benzylpenicillin and results in bacterial death. [2] [3] Procaine makes the combination long acting. [4]
Procaine benzylpenicillin was introduced for medical use in 1948. [3] It is on the World Health Organization's List of Essential Medicines. [5]
Specific indications for procaine penicillin include: [6]
At high doses procaine penicillin can cause seizures and CNS abnormalities due to procaine present in it.[ citation needed]
It is a form of penicillin which is a combination of benzylpenicillin and the local anaesthetic agent procaine. [9] Following deep intramuscular injection, it is slowly absorbed into the circulation and hydrolysed to benzylpenicillin — thus it is used where prolonged low concentrations of benzylpenicillin are required.