Clinical data | |
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Trade names | Naxcel |
AHFS/ Drugs.com | International Drug Names |
ATCvet code | |
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ChemSpider | |
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ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C19H17N5O7S3 |
Molar mass | 523.55 g·mol−1 |
3D model ( JSmol) | |
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(verify) |
Ceftiofur is an antibiotic of the cephalosporin type ( third generation), licensed for use in veterinary medicine. It was first described in 1987. [1] It is marketed by pharmaceutical company Zoetis as Excenel, [2] Naxcel, and Excede and is also the active ingredient in that company's Spectramast LC (lactating cow formulation) and Spectramast DC (dry cow formulation) product.[ citation needed]
It is resistant to the antibiotic resistance enzyme beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. [3]
The metabolite desfuroylceftiofur also has antibiotic activity. [4] The two compounds are measured together to measure for antibiotic activity in milk (alongside other antibiotics). [5]
Clinical data | |
---|---|
Trade names | Naxcel |
AHFS/ Drugs.com | International Drug Names |
ATCvet code | |
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C19H17N5O7S3 |
Molar mass | 523.55 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(verify) |
Ceftiofur is an antibiotic of the cephalosporin type ( third generation), licensed for use in veterinary medicine. It was first described in 1987. [1] It is marketed by pharmaceutical company Zoetis as Excenel, [2] Naxcel, and Excede and is also the active ingredient in that company's Spectramast LC (lactating cow formulation) and Spectramast DC (dry cow formulation) product.[ citation needed]
It is resistant to the antibiotic resistance enzyme beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. [3]
The metabolite desfuroylceftiofur also has antibiotic activity. [4] The two compounds are measured together to measure for antibiotic activity in milk (alongside other antibiotics). [5]