Naphthoylindoles are a class of synthetic cannabinoids. [1]
Behaving similarly in vivo to endocannabinoids such as anandamide or 2-arachidonoylglycerol (2-AG), Naphthoylindoles can bind to endocannabinoid receptors in animals, presenting as CB1 and/or CB2 partial/ full agonists.
They have gained notoriety over the years for illicit usage and distribution in Europe and North America, typically marketed as "herbal incense blends." [2]
Naphthoylindoles are a class of synthetic cannabinoids. [1]
Behaving similarly in vivo to endocannabinoids such as anandamide or 2-arachidonoylglycerol (2-AG), Naphthoylindoles can bind to endocannabinoid receptors in animals, presenting as CB1 and/or CB2 partial/ full agonists.
They have gained notoriety over the years for illicit usage and distribution in Europe and North America, typically marketed as "herbal incense blends." [2]
Phytocannabinoids ( comparison) |
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Endocannabinoids |
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Synthetic cannabinoid receptor agonists / neocannabinoids |
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Allosteric CBRTooltip Cannabinoid receptor ligands | |||||||||||||||||||||||||||||||||||||||||||||||||||
Endocannabinoid enhancers (inactivation inhibitors) |
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Anticannabinoids (antagonists/inverse agonists/antibodies) |
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