AMG-36 (part of the
AM cannabinoid series) is an
analgesic drug which is a
cannabinoidagonist. It is a derivative of Δ8-
THC substituted with a
cyclopentane group on the 3-position side chain. AMG-36 is a potent agonist at both
CB1 and
CB2 with moderate selectivity for CB1, with a
Ki of 0.45 nM at CB1 vs 1.92 nM at CB2.[1][2]
AMG-36 (part of the
AM cannabinoid series) is an
analgesic drug which is a
cannabinoidagonist. It is a derivative of Δ8-
THC substituted with a
cyclopentane group on the 3-position side chain. AMG-36 is a potent agonist at both
CB1 and
CB2 with moderate selectivity for CB1, with a
Ki of 0.45 nM at CB1 vs 1.92 nM at CB2.[1][2]