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CAS Number | |
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ChemSpider | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C23H28N2O |
Molar mass | 348.490 g·mol−1 |
3D model ( JSmol) | |
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NMP-7 is a drug which acts as both a non-selective agonist of the CB1 and CB2 cannabinoid receptors, and also as a blocker of T-type calcium channels, the target of anticonvulsant drugs such as ethosuximide. NMP-7 has an agonist EC50 of 96.9nM at CB1 and 10.5nM at CB2, and an IC50 of 1.84μM for blocking Cav3.2 T-type calcium channels. In animal studies it produces potent analgesic effects in a variety of different tests. [1]
![]() | This cannabinoid related article is a stub. You can help Wikipedia by expanding it. |
![]() | |
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C23H28N2O |
Molar mass | 348.490 g·mol−1 |
3D model ( JSmol) | |
| |
|
NMP-7 is a drug which acts as both a non-selective agonist of the CB1 and CB2 cannabinoid receptors, and also as a blocker of T-type calcium channels, the target of anticonvulsant drugs such as ethosuximide. NMP-7 has an agonist EC50 of 96.9nM at CB1 and 10.5nM at CB2, and an IC50 of 1.84μM for blocking Cav3.2 T-type calcium channels. In animal studies it produces potent analgesic effects in a variety of different tests. [1]
Phytocannabinoids ( comparison) |
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Endocannabinoids |
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Synthetic cannabinoid receptor agonists / neocannabinoids |
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Allosteric CBRTooltip Cannabinoid receptor ligands | |||||||||||||||||||||||||||||||||||||||||
Endocannabinoid enhancers (inactivation inhibitors) |
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Anticannabinoids (antagonists/inverse agonists/antibodies) |
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![]() | This cannabinoid related article is a stub. You can help Wikipedia by expanding it. |