Serine/threonine-protein kinase WNK3, also known as protein kinase lysine-deficient 3, is a
protein that in humans is encoded by the WNK3gene.[5]
Function
WNK3 is a protein belonging to the 'with no lysine' family of
serine-threonine protein kinases. These family members lack the catalytic
lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular
Ca2+ transport pathway, and it plays a role in the increase of cell survival in a
caspase 3 dependent pathway.[5]
Auffray C, Behar G, Bois F, et al. (1995). "[IMAGE: molecular integration of the analysis of the human genome and its expression]". Comptes Rendus de l'Académie des Sciences, Série III. 318 (2): 263–72.
PMID7757816.
Holden S, Cox J, Raymond FL (2004). "Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3)". Gene. 335: 109–19.
doi:
10.1016/j.gene.2004.03.009.
PMID15194194.
Serine/threonine-protein kinase WNK3, also known as protein kinase lysine-deficient 3, is a
protein that in humans is encoded by the WNK3gene.[5]
Function
WNK3 is a protein belonging to the 'with no lysine' family of
serine-threonine protein kinases. These family members lack the catalytic
lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular
Ca2+ transport pathway, and it plays a role in the increase of cell survival in a
caspase 3 dependent pathway.[5]
Auffray C, Behar G, Bois F, et al. (1995). "[IMAGE: molecular integration of the analysis of the human genome and its expression]". Comptes Rendus de l'Académie des Sciences, Série III. 318 (2): 263–72.
PMID7757816.
Holden S, Cox J, Raymond FL (2004). "Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3)". Gene. 335: 109–19.
doi:
10.1016/j.gene.2004.03.009.
PMID15194194.