Death-associated protein kinase 3 is an
enzyme that in humans is encoded by the DAPK3gene.[5][6]
Function
Death-associated protein kinase 3 (DAPK3) induces
morphological changes in
apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis.[6]
Unlike most other mammalian genes, murine (rat and mouse) DAPK3 has undergone accelerated evolution and diverged from the tightly conserved consensus that is maintained from fish to human.[7]
Burch LR, Scott M, Pohler E, Meek D, Hupp T (Mar 2004). "Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1". Journal of Molecular Biology. 337 (1): 115–28.
doi:
10.1016/j.jmb.2003.10.081.
PMID15001356.
Death-associated protein kinase 3 is an
enzyme that in humans is encoded by the DAPK3gene.[5][6]
Function
Death-associated protein kinase 3 (DAPK3) induces
morphological changes in
apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis.[6]
Unlike most other mammalian genes, murine (rat and mouse) DAPK3 has undergone accelerated evolution and diverged from the tightly conserved consensus that is maintained from fish to human.[7]
Burch LR, Scott M, Pohler E, Meek D, Hupp T (Mar 2004). "Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1". Journal of Molecular Biology. 337 (1): 115–28.
doi:
10.1016/j.jmb.2003.10.081.
PMID15001356.