This list contains a list of
EC numbers for the sixth group, EC 6,
ligases, placed in numerical order as determined by the Nomenclature Committee of the
International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee.[1] The database is developed and maintained by Andrew McDonald.[2]
EC 6.1.1.28: proline/cysteine—tRNA ligase. Later published work having demonstrated that this was not a genuine enzyme, EC 6.1.1.28 was withdrawn at the public-review stage before being made official
EC 6.3.1.16: The enzyme was discovered at the public-review stage to have been misclassified and so was withdrawn. See
EC6.3.3.6, carbapenam-3-carboxylate synthase
EC 6.3.2.19: The ubiquitinylation process is now known to be performed by several enzymes in sequence, starting with
EC6.2.1.45 (ubiquitin-activating enzyme E1) and followed by several transfer reactions, including those of
EC2.3.2.23 (E2 ubiquitin-conjugating enzyme) and
EC2.3.2.27 (RING-type E3 ubiquitin transferase)
EC 6.3.2.21: The reaction is performed by the sequential action of
EC6.2.1.45 (ubiquitin-activating enzyme E1), several ubiquitin transferases and finally by
EC2.3.2.27 [ubiquitin transferase RING E3 (calmodulin-selective)]
EC 6.3.2.22: Now
EC6.3.1.14, diphthine—ammonia ligase.
EC 6.3.2.27: The activity is covered by two independent enzymes,
EC6.3.2.38N2-citryl-N6-acetyl-N6-hydroxylysine synthase, and
EC6.3.2.39, aerobactin synthase
EC 6.3.2.28: Now
EC6.3.2.49, L-alanine-L-anticapsin ligase
EC 6.3.5.8: Now
EC2.6.1.85, aminodeoxychorismate synthase. As ATP is not hydrolysed during the reaction, the classification of the enzyme as a ligase was incorrect
This list contains a list of
EC numbers for the sixth group, EC 6,
ligases, placed in numerical order as determined by the Nomenclature Committee of the
International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee.[1] The database is developed and maintained by Andrew McDonald.[2]
EC 6.1.1.28: proline/cysteine—tRNA ligase. Later published work having demonstrated that this was not a genuine enzyme, EC 6.1.1.28 was withdrawn at the public-review stage before being made official
EC 6.3.1.16: The enzyme was discovered at the public-review stage to have been misclassified and so was withdrawn. See
EC6.3.3.6, carbapenam-3-carboxylate synthase
EC 6.3.2.19: The ubiquitinylation process is now known to be performed by several enzymes in sequence, starting with
EC6.2.1.45 (ubiquitin-activating enzyme E1) and followed by several transfer reactions, including those of
EC2.3.2.23 (E2 ubiquitin-conjugating enzyme) and
EC2.3.2.27 (RING-type E3 ubiquitin transferase)
EC 6.3.2.21: The reaction is performed by the sequential action of
EC6.2.1.45 (ubiquitin-activating enzyme E1), several ubiquitin transferases and finally by
EC2.3.2.27 [ubiquitin transferase RING E3 (calmodulin-selective)]
EC 6.3.2.22: Now
EC6.3.1.14, diphthine—ammonia ligase.
EC 6.3.2.27: The activity is covered by two independent enzymes,
EC6.3.2.38N2-citryl-N6-acetyl-N6-hydroxylysine synthase, and
EC6.3.2.39, aerobactin synthase
EC 6.3.2.28: Now
EC6.3.2.49, L-alanine-L-anticapsin ligase
EC 6.3.5.8: Now
EC2.6.1.85, aminodeoxychorismate synthase. As ATP is not hydrolysed during the reaction, the classification of the enzyme as a ligase was incorrect