Ononetin is a natural product from the deoxybenzoin group, which is found in the Russian traditional medicine plant Ononis spinosa. It acts as an inhibitor of the transient receptor potential ion channel
TRPM3 and has
analgesic effects in animal studies,[1][2] as well as being used for research into the role of TRPM3 in the
immune system dysfunction associated with
chronic fatigue syndrome.[3][4]
^Straub I, Krügel U, Mohr F, Teichert J, Rizun O, Konrad M, et al. (November 2013). "Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo". Molecular Pharmacology. 84 (5): 736–50.
doi:
10.1124/mol.113.086843.
PMID24006495.
S2CID20522738.
Ononetin is a natural product from the deoxybenzoin group, which is found in the Russian traditional medicine plant Ononis spinosa. It acts as an inhibitor of the transient receptor potential ion channel
TRPM3 and has
analgesic effects in animal studies,[1][2] as well as being used for research into the role of TRPM3 in the
immune system dysfunction associated with
chronic fatigue syndrome.[3][4]
^Straub I, Krügel U, Mohr F, Teichert J, Rizun O, Konrad M, et al. (November 2013). "Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo". Molecular Pharmacology. 84 (5): 736–50.
doi:
10.1124/mol.113.086843.
PMID24006495.
S2CID20522738.