| |||
Names | |||
---|---|---|---|
Preferred IUPAC name
4-Isopropylbenzaldehyde | |||
Systematic IUPAC name
4-(1-Methylethyl)benzenecarbaldehyde | |||
Other names
p-Isopropylbenzaldehyde
4-(1-Methylethyl)benzaldehyde Cuminal Cumaldehyde | |||
Identifiers | |||
3D model (
JSmol)
|
|||
ChEBI | |||
ChEMBL | |||
ChemSpider | |||
ECHA InfoCard | 100.004.107 | ||
EC Number |
| ||
KEGG | |||
PubChem
CID
|
|||
RTECS number |
| ||
UNII | |||
CompTox Dashboard (
EPA)
|
|||
| |||
| |||
Properties | |||
C10H12O | |||
Molar mass | 148.205 g·mol−1 | ||
Appearance | Colorless oil | ||
Density | 0.978 g/cm3 | ||
Boiling point | 235.5 °C (455.9 °F; 508.6 K) | ||
Insoluble | |||
Hazards | |||
GHS labelling: | |||
Warning | |||
H302, H317 | |||
P261, P264, P270, P272, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, P501 | |||
NFPA 704 (fire diamond) | |||
Flash point | 93 °C (199 °F; 366 K) | ||
Related compounds | |||
Related compounds
|
Benzaldehyde Cumene Cuminol | ||
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Cuminaldehyde (4-isopropylbenzaldehyde) is a natural organic compound with the molecular formula C10H12O. It is a benzaldehyde with an isopropyl group substituted in the 4-position.
Cuminaldehyde is a constituent of the essential oils of eucalyptus, myrrh, cassia, cumin, and others. [1] It has a pleasant smell and contributes to the aroma of these oils. It is used commercially in perfumes and other cosmetics.
It has been shown that cuminaldehyde, as a small molecule, inhibits the fibrillation of alpha-synuclein, [2] which, if aggregated, forms insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy bodies [3] and multiple system atrophy. [4]
Cuminaldehyde can be prepared synthetically by the reduction of 4-isopropylbenzoyl chloride or by the formylation of cumene.
The thiosemicarbazone of cuminaldehyde has antiviral properties.[ medical citation needed]
| |||
Names | |||
---|---|---|---|
Preferred IUPAC name
4-Isopropylbenzaldehyde | |||
Systematic IUPAC name
4-(1-Methylethyl)benzenecarbaldehyde | |||
Other names
p-Isopropylbenzaldehyde
4-(1-Methylethyl)benzaldehyde Cuminal Cumaldehyde | |||
Identifiers | |||
3D model (
JSmol)
|
|||
ChEBI | |||
ChEMBL | |||
ChemSpider | |||
ECHA InfoCard | 100.004.107 | ||
EC Number |
| ||
KEGG | |||
PubChem
CID
|
|||
RTECS number |
| ||
UNII | |||
CompTox Dashboard (
EPA)
|
|||
| |||
| |||
Properties | |||
C10H12O | |||
Molar mass | 148.205 g·mol−1 | ||
Appearance | Colorless oil | ||
Density | 0.978 g/cm3 | ||
Boiling point | 235.5 °C (455.9 °F; 508.6 K) | ||
Insoluble | |||
Hazards | |||
GHS labelling: | |||
Warning | |||
H302, H317 | |||
P261, P264, P270, P272, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, P501 | |||
NFPA 704 (fire diamond) | |||
Flash point | 93 °C (199 °F; 366 K) | ||
Related compounds | |||
Related compounds
|
Benzaldehyde Cumene Cuminol | ||
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Cuminaldehyde (4-isopropylbenzaldehyde) is a natural organic compound with the molecular formula C10H12O. It is a benzaldehyde with an isopropyl group substituted in the 4-position.
Cuminaldehyde is a constituent of the essential oils of eucalyptus, myrrh, cassia, cumin, and others. [1] It has a pleasant smell and contributes to the aroma of these oils. It is used commercially in perfumes and other cosmetics.
It has been shown that cuminaldehyde, as a small molecule, inhibits the fibrillation of alpha-synuclein, [2] which, if aggregated, forms insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy bodies [3] and multiple system atrophy. [4]
Cuminaldehyde can be prepared synthetically by the reduction of 4-isopropylbenzoyl chloride or by the formylation of cumene.
The thiosemicarbazone of cuminaldehyde has antiviral properties.[ medical citation needed]