From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Potassium channel subfamily T, member 1 , also known as KCNT1 is a human
gene that encodes the KCa 4.1 protein. KCa 4.1 is a member of the
calcium-activated potassium channel protein family
[5]
Associated Conditions
Mutations in the KCNT1 gene has been shown to be a cause of
Early Infantile Epileptic Encephalopathy .
[6]
See also
References
Further reading
Nagase T, Kikuno R, Ishikawa KI, et al. (2000).
"Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 7 (1): 65–73.
doi :
10.1093/dnares/7.1.65 .
PMID
10718198 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2002).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65.
doi :
10.1101/gr.4039406 .
PMC
1356129 .
PMID
16344560 .
Humphray SJ, Oliver K, Hunt AR, et al. (2004).
"DNA sequence and analysis of human chromosome 9" . Nature . 429 (6990): 369–74.
Bibcode :
2004Natur.429..369H .
doi :
10.1038/nature02465 .
PMC
2734081 .
PMID
15164053 .
Wei AD, Gutman GA, Aldrich R, et al. (2005). "International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels". Pharmacol. Rev . 57 (4): 463–72.
doi :
10.1124/pr.57.4.9 .
PMID
16382103 .
S2CID
8290401 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .