| |
| Names | |
|---|---|
|
Preferred IUPAC name
3-[(Dimethylcarbamoyl)oxy]-N,N-diethyl-N-methylanilinium iodide | |
| Other names
Substance 3393
| |
| Identifiers | |
3D model (
JSmol)
|
|
| ChemSpider | |
PubChem
CID
|
|
| UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
| Properties | |
| C14H23IN2O2 | |
| Molar mass | 378.254 g·mol−1 |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
|
Extremely toxic |
| Lethal dose or concentration (LD, LC): | |
LD50 (
median dose)
|
175 μg/kg (subcutaneous, mice)
[1] 89 μg/kg (intravenous, mice) [1] 60 μg/kg (intravenous, mice) [2] |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
| |
TL-1238 (Substance 3393) is an extremely potent carbamate acetylcholinesterase inhibitor. It has been shown to be more potent than neostigmine. [2] [3]
See also
References
- ^ a b Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
- ^ a b Bülbring, E; Chou, TC (March 1947). "The relative activity of prostigmine homologues and other substances as antagonists to tubocurarine". British Journal of Pharmacology and Chemotherapy. 2 (1): 8–22. doi: 10.1111/j.1476-5381.1947.tb00316.x. PMC 1509759. PMID 19108106.
- ^ BLASCHKO, H; BULBRING, E; CHOU, TC (March 1949). "Tubocurarine antagonism and inhibition of cholinesterases". British Journal of Pharmacology and Chemotherapy. 4 (1): 29–32. doi: 10.1111/j.1476-5381.1949.tb00512.x. PMC 1509899. PMID 18113150.
 | This article about an ester is a stub. You can help Wikipedia by expanding it. |
|
| |
| Names | |
|---|---|
|
Preferred IUPAC name
3-[(Dimethylcarbamoyl)oxy]-N,N-diethyl-N-methylanilinium iodide | |
| Other names
Substance 3393
| |
| Identifiers | |
3D model (
JSmol)
|
|
| ChemSpider | |
PubChem
CID
|
|
| UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
| Properties | |
| C14H23IN2O2 | |
| Molar mass | 378.254 g·mol−1 |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
|
Extremely toxic |
| Lethal dose or concentration (LD, LC): | |
LD50 (
median dose)
|
175 μg/kg (subcutaneous, mice)
[1] 89 μg/kg (intravenous, mice) [1] 60 μg/kg (intravenous, mice) [2] |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
| |
TL-1238 (Substance 3393) is an extremely potent carbamate acetylcholinesterase inhibitor. It has been shown to be more potent than neostigmine. [2] [3]
See also
References
- ^ a b Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
- ^ a b Bülbring, E; Chou, TC (March 1947). "The relative activity of prostigmine homologues and other substances as antagonists to tubocurarine". British Journal of Pharmacology and Chemotherapy. 2 (1): 8–22. doi: 10.1111/j.1476-5381.1947.tb00316.x. PMC 1509759. PMID 19108106.
- ^ BLASCHKO, H; BULBRING, E; CHOU, TC (March 1949). "Tubocurarine antagonism and inhibition of cholinesterases". British Journal of Pharmacology and Chemotherapy. 4 (1): 29–32. doi: 10.1111/j.1476-5381.1949.tb00512.x. PMC 1509899. PMID 18113150.
|
| This article about an ester is a stub. You can help Wikipedia by expanding it. |