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Names | |
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IUPAC name
(2S,6R,14S,E)-5-ethylidene-14-(hydroxymethyl)-3,14-dimethyl-2,3,4,5,6,7-hexahydro-1H-2,6-methanoazecino[5,4-b]indol-8(9H)-one
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Other names
17-hydroxy-vobasan-3-one,
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Identifiers | |
3D model (
JSmol)
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ChemSpider | |
PubChem
CID
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CompTox Dashboard (
EPA)
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Properties | |
C20H24N2O2 | |
Molar mass | 324.424 g·mol−1 |
Melting point | 265°C (decomp.) [1] |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Affinine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus Tabernaemontana. [1] [2] Structurally it can be considered a member of the vobasine alkaloid family and may be synthesized from tryptophan. [3] Limited pharmacological testing has indicated that it may be an effective inhibitor of both acetylcholinesterase and butyrylcholinesterase. [4]
![]() | |
Names | |
---|---|
IUPAC name
(2S,6R,14S,E)-5-ethylidene-14-(hydroxymethyl)-3,14-dimethyl-2,3,4,5,6,7-hexahydro-1H-2,6-methanoazecino[5,4-b]indol-8(9H)-one
| |
Other names
17-hydroxy-vobasan-3-one,
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C20H24N2O2 | |
Molar mass | 324.424 g·mol−1 |
Melting point | 265°C (decomp.) [1] |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Affinine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus Tabernaemontana. [1] [2] Structurally it can be considered a member of the vobasine alkaloid family and may be synthesized from tryptophan. [3] Limited pharmacological testing has indicated that it may be an effective inhibitor of both acetylcholinesterase and butyrylcholinesterase. [4]