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Names | |
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IUPAC name
1-Methylsarpagan-17-ol
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Systematic IUPAC name
[(6S,9E,10R,11R,12S)-9-Ethylidene-5-methyl-5,6,7,8,9,10,11,11a,12-decahydro-6,10-methanoindolo[2,3-g]quinolizin-11-yl]methanol | |
Other names
De(hydroxymethyl)voachalotinol
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Identifiers | |
3D model (
JSmol)
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ChemSpider | |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C20H24N2O | |
Molar mass | 308.425 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Affinisine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus Tabernaemontana. [1] [2] Structurally, it can be considered a member of the sarpagine alkaloid family and may be synthesized from tryptophan via a Pictet-Spengler reaction. [3] [4]
Limited pharmacological testing has indicated that affinisine may effectively inhibit acetylcholinesterase and butyrylcholinesterase. [1] [5]
![]() | |
Names | |
---|---|
IUPAC name
1-Methylsarpagan-17-ol
| |
Systematic IUPAC name
[(6S,9E,10R,11R,12S)-9-Ethylidene-5-methyl-5,6,7,8,9,10,11,11a,12-decahydro-6,10-methanoindolo[2,3-g]quinolizin-11-yl]methanol | |
Other names
De(hydroxymethyl)voachalotinol
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C20H24N2O | |
Molar mass | 308.425 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Affinisine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus Tabernaemontana. [1] [2] Structurally, it can be considered a member of the sarpagine alkaloid family and may be synthesized from tryptophan via a Pictet-Spengler reaction. [3] [4]
Limited pharmacological testing has indicated that affinisine may effectively inhibit acetylcholinesterase and butyrylcholinesterase. [1] [5]