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Clinical data | |
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Routes of administration | Oral |
ATC code |
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Legal status | |
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Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.034.939 |
Chemical and physical data | |
Formula | C34H38N4O6 |
Molar mass | 598.700 g·mol−1 |
3D model ( JSmol) | |
Melting point | 172.5 °C (342.5 °F) |
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Hematoporphyrin (Photodyn, Sensibion) is a porphyrin prepared from hemin. It is a derivative of protoporphyrin IX, where the two vinyl groups have been hydrated (converted to alcohols). It is a deeply colored solid that is usually encountered as a solution. Its chemical structure was determined in 1900. [1]
It is used as a photosensitizer in photodynamic therapy. Acetylation of hematoporphyrin followed by hydrolysis of the product of that reaction affords a mixture called hematoporphyrin derivative (HPD), which is also used in photodynamic therapy. [2]
Hematoporphyrin has also been used as an antidepressant and antipsychotic since the 1920s. [3] [4]
![]() | |
Clinical data | |
---|---|
Routes of administration | Oral |
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.034.939 |
Chemical and physical data | |
Formula | C34H38N4O6 |
Molar mass | 598.700 g·mol−1 |
3D model ( JSmol) | |
Melting point | 172.5 °C (342.5 °F) |
| |
| |
(verify) |
Hematoporphyrin (Photodyn, Sensibion) is a porphyrin prepared from hemin. It is a derivative of protoporphyrin IX, where the two vinyl groups have been hydrated (converted to alcohols). It is a deeply colored solid that is usually encountered as a solution. Its chemical structure was determined in 1900. [1]
It is used as a photosensitizer in photodynamic therapy. Acetylation of hematoporphyrin followed by hydrolysis of the product of that reaction affords a mixture called hematoporphyrin derivative (HPD), which is also used in photodynamic therapy. [2]
Hematoporphyrin has also been used as an antidepressant and antipsychotic since the 1920s. [3] [4]