| Dynamin superfamily | |
|---|---|
| Identifiers | |
| Symbol | DSP |
| InterPro | IPR022812 |
Dynamin Superfamily Protein (DSP) is a protein superfamily includes classical dynamins, GBPs, Mx proteins, OPA1, mitofusins in Eukaryote, and bacterial dynamin-like proteins (BDLPs) in Prokaryote. [1] DSPs mediate eukaryotic membrane fusion and fission necessary for endocytosis, organelle biogenesis and maintenance, Mitochondrial fusion and fission, as well as for prokaryotic cytokinesis. [2]
Structure
All DSPs have two common domains: a GTPase domain and an elongated α-helical bundle domain. [2]
References
- ^ Henley JR, Cao H, McNiven MA (December 1999). "Participation of dynamin in the biogenesis of cytoplasmic vesicles". FASEB Journal. 13 Suppl 2 (9002): S243-7. doi: 10.1096/fasebj.13.9002.S243. PMID 10619136. S2CID 24401725.
- ^ a b Jimah, JR; Hinshaw, JE (March 2019). "Structural Insights into the Mechanism of Dynamin Superfamily Proteins". Trends in Cell Biology. 29 (3): 257–273. doi: 10.1016/j.tcb.2018.11.003. PMC 9623552. PMID 30527453. S2CID 54478789.
External links
| Dynamin superfamily | |
|---|---|
| Identifiers | |
| Symbol | DSP |
| InterPro | IPR022812 |
Dynamin Superfamily Protein (DSP) is a protein superfamily includes classical dynamins, GBPs, Mx proteins, OPA1, mitofusins in Eukaryote, and bacterial dynamin-like proteins (BDLPs) in Prokaryote. [1] DSPs mediate eukaryotic membrane fusion and fission necessary for endocytosis, organelle biogenesis and maintenance, Mitochondrial fusion and fission, as well as for prokaryotic cytokinesis. [2]
Structure
All DSPs have two common domains: a GTPase domain and an elongated α-helical bundle domain. [2]
References
- ^ Henley JR, Cao H, McNiven MA (December 1999). "Participation of dynamin in the biogenesis of cytoplasmic vesicles". FASEB Journal. 13 Suppl 2 (9002): S243-7. doi: 10.1096/fasebj.13.9002.S243. PMID 10619136. S2CID 24401725.
- ^ a b Jimah, JR; Hinshaw, JE (March 2019). "Structural Insights into the Mechanism of Dynamin Superfamily Proteins". Trends in Cell Biology. 29 (3): 257–273. doi: 10.1016/j.tcb.2018.11.003. PMC 9623552. PMID 30527453. S2CID 54478789.