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Sulfafurazole

Clinical data
AHFS/ Drugs.com	International Drug Names
MedlinePlus	a601049
Pregnancy category	To be avoided within two months of term
Routes of administration	Oral
ATC code	J01EB05 ( WHO) S01AB02 ( WHO) QJ01EQ05 ( WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Excretion	Excreted unchanged in urine
Identifiers
IUPAC name 4-Amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
CAS Number	127-69-5 Y
PubChem CID	5344
DrugBank	DB00263 N
ChemSpider	5151
UNII	740T4C525W
KEGG	D00450 Y
ChEMBL	ChEMBL453 N
CompTox Dashboard ( EPA)	DTXSID6021292
ECHA InfoCard	100.004.418
Chemical and physical data
Formula	C11H13N3O3S
Molar mass	267.30 g·mol−1
3D model ( JSmol)	Interactive image
Melting point	194 °C (381 °F)
SMILES CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N
InChI InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3 Key:NHUHCSRWZMLRLA-UHFFFAOYSA-N
NY  (what is this?)   (verify)

Sulfafurazole ( INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an dimethyl- isoxazole substituent. It possesses antibiotic activity against a wide range of Gram-negative and Gram-positive organisms. It is sometimes given in combination with erythromycin (see erythromycin/Sulfafurazole) or phenazopyridine. It is used locally in a 4% solution or ointment.

References

External links

• Sulfisoxazole at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• MedlinePlus DrugInfo medmaster-a601049
• MedlinePlus DrugInfo medmaster-a601115
• Diseases Database (DDB): 30455

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