This article relies largely or entirely on a
single source. (March 2024) |
Clinical data | |
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ATC code |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.001.131 |
Chemical and physical data | |
Formula | C14H14N2O4S |
Molar mass | 306.34 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(verify) |
Acediasulfone ( INN) is an antimicrobial drug, which also has antimalarial activity. It is a long-acting prodrug of dapsone, which is used for treating leprosy.
Dapsone is somewhat inconvenient to administer to patients because of its rather low water solubility.
In the search for more easily administered drugs, dapsone (1) was reacted with bromoacetic acid to give acediasulfone (2) which can be administered as a water-soluble salt.
This article relies largely or entirely on a
single source. (March 2024) |
Clinical data | |
---|---|
ATC code |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.001.131 |
Chemical and physical data | |
Formula | C14H14N2O4S |
Molar mass | 306.34 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(verify) |
Acediasulfone ( INN) is an antimicrobial drug, which also has antimalarial activity. It is a long-acting prodrug of dapsone, which is used for treating leprosy.
Dapsone is somewhat inconvenient to administer to patients because of its rather low water solubility.
In the search for more easily administered drugs, dapsone (1) was reacted with bromoacetic acid to give acediasulfone (2) which can be administered as a water-soluble salt.