PIPEMIDIC ACID

Pipemidic acid
Clinical data
AHFS/ Drugs.com	International Drug Names
ATC code	J01MB04 ( WHO) ;
Identifiers
	IUPAC name 8-Ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid;
CAS Number	51940-44-4;
PubChem CID	4831;
ChemSpider	4665;
UNII	LT12J5HVR8;
KEGG	D08379;
ChEBI	CHEBI:75250;
ChEMBL	ChEMBL30116;
CompTox Dashboard ( EPA)	DTXSID3023479 ;
ECHA InfoCard	100.052.283
Chemical and physical data
Formula	C14H17N5O3
Molar mass	303.322 g·mol−1
3D model ( JSmol)	Interactive image;
	SMILES CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCNCC3)C(=O)O;
	InChI InChI=1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22); Key:JOHZPMXAZQZXHR-UHFFFAOYSA-N;

Pipemidic acid is a member of the pyridopyrimidine class of antibacterials, which display some overlap in mechanism of action with analogous pyridone-containing quinolones. It was introduced in 1979 and is active against gram negative and some gram positive bacteria. It was used for gastrointestinal, biliary, and urinary infections.^[1] The marketing authorization of pipemidic acid has been suspended throughout the EU.^[2]

References

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Clinical data

AHFS/ Drugs.com	International Drug Names
ATC code	J01MB04 ( WHO)
Identifiers
IUPAC name 8-Ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
CAS Number	51940-44-4
PubChem CID	4831
ChemSpider	4665
UNII	LT12J5HVR8
KEGG	D08379
ChEBI	CHEBI:75250
ChEMBL	ChEMBL30116
CompTox Dashboard ( EPA)	DTXSID3023479
ECHA InfoCard	100.052.283
Chemical and physical data
Formula	C₁₄H₁₇N₅O₃
Molar mass	303.322 g·mol⁻¹
3D model ( JSmol)	Interactive image
SMILES CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCNCC3)C(=O)O
InChI InChI=1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22) Key:JOHZPMXAZQZXHR-UHFFFAOYSA-N