From Wikipedia, the free encyclopedia
Small nucleolar RNA snR55/Z10
Predicted secondary structure and sequence conservation of snosnR55
Identifiers
SymbolsnosnR55
Rfam RF00472
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000593
PDB structures PDBe

In molecular biology, Small nucleolar RNA snR55/Z10 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis of other small nuclear RNAs (snRNAs). These small nucleolar RNAs (snoRNAs) are modifying RNAs and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.

snoRNA snR55 was identified in ( Schizosaccharomyces pombe) and has also been called snoRNA Z10. [1] This snoRNA belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O- methylation of substrate RNAs. [2]

This predicted snoRNA does not appear to have the C/D box snoRNA terminal stem structure.

References

  1. ^ Lowe TM, Eddy SR (February 1999). "A computational screen for methylation guide snoRNAs in yeast". Science. 283 (5405): 1168–71. Bibcode: 1999Sci...283.1168L. doi: 10.1126/science.283.5405.1168. PMID  10024243.
  2. ^ Galardi S, Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I (October 2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Molecular and Cellular Biology. 22 (19): 6663–8. doi: 10.1128/MCB.22.19.6663-6668.2002. PMC  134041. PMID  12215523.

External links

From Wikipedia, the free encyclopedia
Small nucleolar RNA snR55/Z10
Predicted secondary structure and sequence conservation of snosnR55
Identifiers
SymbolsnosnR55
Rfam RF00472
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000593
PDB structures PDBe

In molecular biology, Small nucleolar RNA snR55/Z10 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis of other small nuclear RNAs (snRNAs). These small nucleolar RNAs (snoRNAs) are modifying RNAs and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.

snoRNA snR55 was identified in ( Schizosaccharomyces pombe) and has also been called snoRNA Z10. [1] This snoRNA belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O- methylation of substrate RNAs. [2]

This predicted snoRNA does not appear to have the C/D box snoRNA terminal stem structure.

References

  1. ^ Lowe TM, Eddy SR (February 1999). "A computational screen for methylation guide snoRNAs in yeast". Science. 283 (5405): 1168–71. Bibcode: 1999Sci...283.1168L. doi: 10.1126/science.283.5405.1168. PMID  10024243.
  2. ^ Galardi S, Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I (October 2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Molecular and Cellular Biology. 22 (19): 6663–8. doi: 10.1128/MCB.22.19.6663-6668.2002. PMC  134041. PMID  12215523.

External links


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