From Wikipedia, the free encyclopedia
Small nucleolar RNA psi28S-2876
Predicted secondary structure and sequence conservation of snopsi28S-2876
Identifiers
Symbolsnopsi28S-2876
Rfam RF00541
Other data
RNA type Gene; snRNA; snoRNA; HACA-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000594
PDB structures PDBe

In molecular biology, Small nucleolar RNA psi28S-2876 (also known as snoRNA psi28S-2876) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.

This Drosophila-specific snoRNA is a member of the H/ACA box class of snoRNA and is predicted to be responsible for guiding the modification of uridines 2876 and 2956 to pseudouridine in Drosophila 28S rRNA. [1]

References

  1. ^ Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi: 10.1128/MCB.24.13.5797-5807.2004. PMC  480876. PMID  15199136.

External links


From Wikipedia, the free encyclopedia
Small nucleolar RNA psi28S-2876
Predicted secondary structure and sequence conservation of snopsi28S-2876
Identifiers
Symbolsnopsi28S-2876
Rfam RF00541
Other data
RNA type Gene; snRNA; snoRNA; HACA-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000594
PDB structures PDBe

In molecular biology, Small nucleolar RNA psi28S-2876 (also known as snoRNA psi28S-2876) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.

This Drosophila-specific snoRNA is a member of the H/ACA box class of snoRNA and is predicted to be responsible for guiding the modification of uridines 2876 and 2956 to pseudouridine in Drosophila 28S rRNA. [1]

References

  1. ^ Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi: 10.1128/MCB.24.13.5797-5807.2004. PMC  480876. PMID  15199136.

External links



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