From Wikipedia, the free encyclopedia
Small nucleolar RNA snR54
Predicted secondary structure and sequence conservation of snosnR54
Identifiers
SymbolsnosnR54
Rfam RF00473
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000593
PDB structures PDBe

In molecular biology, snR54 is a non-coding RNA that is a member of the C/D class of snoRNA which contain the C box motif (UGAUGA) and D box motif (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. This snoRNA was first identified by a computational screen followed by experimental verification. [1] This RNA guides the 2'-O-methylation of 18S rRNA. In yeast this snoRNA is found to reside in an intron of the IMD4 gene.

Species distribution

This snoRNA has been identified in both yeasts and Drosophila melanogaster. [2]

References

  1. ^ Kiss T (April 2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell. 109 (2): 145–8. doi: 10.1016/S0092-8674(02)00718-3. PMID  12007400. S2CID  8968788.
  2. ^ Lowe TM, Eddy SR (February 1999). "A computational screen for methylation guide snoRNAs in yeast". Science. 283 (5405): 1168–71. Bibcode: 1999Sci...283.1168L. doi: 10.1126/science.283.5405.1168. PMID  10024243.

External links


From Wikipedia, the free encyclopedia
Small nucleolar RNA snR54
Predicted secondary structure and sequence conservation of snosnR54
Identifiers
SymbolsnosnR54
Rfam RF00473
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000593
PDB structures PDBe

In molecular biology, snR54 is a non-coding RNA that is a member of the C/D class of snoRNA which contain the C box motif (UGAUGA) and D box motif (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. This snoRNA was first identified by a computational screen followed by experimental verification. [1] This RNA guides the 2'-O-methylation of 18S rRNA. In yeast this snoRNA is found to reside in an intron of the IMD4 gene.

Species distribution

This snoRNA has been identified in both yeasts and Drosophila melanogaster. [2]

References

  1. ^ Kiss T (April 2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell. 109 (2): 145–8. doi: 10.1016/S0092-8674(02)00718-3. PMID  12007400. S2CID  8968788.
  2. ^ Lowe TM, Eddy SR (February 1999). "A computational screen for methylation guide snoRNAs in yeast". Science. 283 (5405): 1168–71. Bibcode: 1999Sci...283.1168L. doi: 10.1126/science.283.5405.1168. PMID  10024243.

External links



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