From Wikipedia, the free encyclopedia
Small nucleolar RNA J26
Identifiers
SymbolsnoJ26
Rfam RF00336
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000593
PDB structures PDBe

In molecular biology, the Small nucleolar RNA J26 is a non-coding RNA (ncRNA) molecule identified in rice ( Oryza sativa) which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

J26 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O- methylation of substrate RNAs. [1] [2]

References

  1. ^ Galardi S, Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I (October 2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Molecular and Cellular Biology. 22 (19): 6663–8. doi: 10.1128/MCB.22.19.6663-6668.2002. PMC  134041. PMID  12215523.
  2. ^ Kiss T (April 2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell. 109 (2): 145–8. doi: 10.1016/S0092-8674(02)00718-3. PMID  12007400. S2CID  8968788.

External links


From Wikipedia, the free encyclopedia
Small nucleolar RNA J26
Identifiers
SymbolsnoJ26
Rfam RF00336
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000593
PDB structures PDBe

In molecular biology, the Small nucleolar RNA J26 is a non-coding RNA (ncRNA) molecule identified in rice ( Oryza sativa) which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

J26 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O- methylation of substrate RNAs. [1] [2]

References

  1. ^ Galardi S, Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I (October 2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Molecular and Cellular Biology. 22 (19): 6663–8. doi: 10.1128/MCB.22.19.6663-6668.2002. PMC  134041. PMID  12215523.
  2. ^ Kiss T (April 2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell. 109 (2): 145–8. doi: 10.1016/S0092-8674(02)00718-3. PMID  12007400. S2CID  8968788.

External links



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