| Small nucleolar RNA SNORA35 | |
|---|---|
 Predicted
secondary structure and
sequence conservation of SNORA35 | |
| Identifiers | |
| Symbol | SNORA35 |
| Alt. Symbols | snoHBI-36 |
| Rfam | RF00566 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; HACA-box |
| Domain(s) | Eukaryota |
| GO | GO:0006396 GO:0005730 |
| SO | SO:0000594 |
| PDB structures | PDBe |
In molecular biology, for Homo sapiens snoRA35 (also known as HBI-36) is an H/ACA box snoRNA, first cloned from a mouse adult brain cDNA library by Cavaillé et al. (2000), [1] and found to be specifically expressed in the choroid plexus. Its human orthologue, HBI-36 was discovered by a homology search, and was found to be specifically expressed in the brain. Its gene resides in the second intron of the serotonin receptor 2c (5HT-2c) gene, which is predominantly expressed in choroid plexus epithelial cells. The human 5HT-2c mRNA was predicted to be 2'O-methylated by the C/D box snoRNP HBII-52 at a position also subjected to A:I editing. HBI-36 has no documented RNA target.
References
- ^ Cavaillé J, Buiting K, Kiefmann M, Lalande M, Brannan CI, Horsthemke B, Bachellerie JP, Brosius J, Hüttenhofer A (December 2000). "Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization". Proceedings of the National Academy of Sciences of the United States of America. 97 (26): 14311–6. doi: 10.1073/pnas.250426397. PMC 18915. PMID 11106375.
External links
 | This molecular or cell biology article is a stub. You can help Wikipedia by expanding it. |
| Small nucleolar RNA SNORA35 | |
|---|---|
|
Predicted
secondary structure and
sequence conservation of SNORA35 | |
| Identifiers | |
| Symbol | SNORA35 |
| Alt. Symbols | snoHBI-36 |
| Rfam | RF00566 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; HACA-box |
| Domain(s) | Eukaryota |
| GO | GO:0006396 GO:0005730 |
| SO | SO:0000594 |
| PDB structures | PDBe |
In molecular biology, for Homo sapiens snoRA35 (also known as HBI-36) is an H/ACA box snoRNA, first cloned from a mouse adult brain cDNA library by Cavaillé et al. (2000), [1] and found to be specifically expressed in the choroid plexus. Its human orthologue, HBI-36 was discovered by a homology search, and was found to be specifically expressed in the brain. Its gene resides in the second intron of the serotonin receptor 2c (5HT-2c) gene, which is predominantly expressed in choroid plexus epithelial cells. The human 5HT-2c mRNA was predicted to be 2'O-methylated by the C/D box snoRNP HBII-52 at a position also subjected to A:I editing. HBI-36 has no documented RNA target.
References
- ^ Cavaillé J, Buiting K, Kiefmann M, Lalande M, Brannan CI, Horsthemke B, Bachellerie JP, Brosius J, Hüttenhofer A (December 2000). "Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization". Proceedings of the National Academy of Sciences of the United States of America. 97 (26): 14311–6. doi: 10.1073/pnas.250426397. PMC 18915. PMID 11106375.
External links
|
| This molecular or cell biology article is a stub. You can help Wikipedia by expanding it. |