Solute carrier family 6, member 18 also known as SLC6A18 is a
protein which in humans is encoded by the SLC6A18gene.[5][6]
Function
The SLC6 family of proteins, which includes SLC6A18, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions.[6][7]
^
abHöglund PJ, Adzic D, Scicluna SJ, Lindblom J, Fredriksson R (October 2005). "The repertoire of solute carriers of family 6: identification of new human and rodent genes". Biochem. Biophys. Res. Commun. 336 (1): 175–89.
doi:
10.1016/j.bbrc.2005.08.048.
PMID16125675.
Bröer S (2008). "Amino acid transport across mammalian intestinal and renal epithelia". Physiol. Rev. 88 (1): 249–86.
doi:
10.1152/physrev.00018.2006.
PMID18195088.
Yoon YH, Seol SY, Heo J, et al. (2008). "Analysis of VNTRs in the solute carrier family 6, member 18 (SLC6A18) and lack of association with hypertension". DNA Cell Biol. 27 (10): 559–67.
doi:
10.1089/dna.2008.0755.
PMID18554081.
Solute carrier family 6, member 18 also known as SLC6A18 is a
protein which in humans is encoded by the SLC6A18gene.[5][6]
Function
The SLC6 family of proteins, which includes SLC6A18, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions.[6][7]
^
abHöglund PJ, Adzic D, Scicluna SJ, Lindblom J, Fredriksson R (October 2005). "The repertoire of solute carriers of family 6: identification of new human and rodent genes". Biochem. Biophys. Res. Commun. 336 (1): 175–89.
doi:
10.1016/j.bbrc.2005.08.048.
PMID16125675.
Bröer S (2008). "Amino acid transport across mammalian intestinal and renal epithelia". Physiol. Rev. 88 (1): 249–86.
doi:
10.1152/physrev.00018.2006.
PMID18195088.
Yoon YH, Seol SY, Heo J, et al. (2008). "Analysis of VNTRs in the solute carrier family 6, member 18 (SLC6A18) and lack of association with hypertension". DNA Cell Biol. 27 (10): 559–67.
doi:
10.1089/dna.2008.0755.
PMID18554081.