Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of
prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human
megakaryocytes.[8]
Kanaoka Y, Urade Y (2004). "Hematopoietic prostaglandin D synthase". Prostaglandins Leukot. Essent. Fatty Acids. 69 (2–3): 163–7.
doi:
10.1016/S0952-3278(03)00077-2.
PMID12895599.
Suzuki T, Watanabe K, Kanaoka Y, et al. (1998). "Induction of hematopoietic prostaglandin D synthase in human megakaryocytic cells by phorbol ester". Biochem. Biophys. Res. Commun. 241 (2): 288–93.
doi:
10.1006/bbrc.1997.7803.
PMID9425264.
Sui D, Wilson JE (2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase". Arch. Biochem. Biophys. 382 (2): 262–74.
doi:
10.1006/abbi.2000.2019.
PMID11068878.
Noguchi E, Shibasaki M, Kamioka M, et al. (2002). "New polymorphisms of haematopoietic prostaglandin D synthase and human prostanoid DP receptor genes". Clin. Exp. Allergy. 32 (1): 93–6.
doi:
10.1046/j.0022-0477.2001.01261.x.
PMID12002745.
S2CID24779233.
Inoue T, Irikura D, Okazaki N, et al. (2003). "Mechanism of metal activation of human hematopoietic prostaglandin D synthase". Nat. Struct. Biol. 10 (4): 291–6.
doi:
10.1038/nsb907.
PMID12627223.
S2CID25214344.
Ando M, Murakami Y, Kojima F, et al. (2003). "Retrovirally introduced prostaglandin D2 synthase suppresses lung injury induced by bleomycin". Am. J. Respir. Cell Mol. Biol. 28 (5): 582–91.
doi:
10.1165/rcmb.2002-0162OC.
PMID12707014.
Inoue T, Okano Y, Kado Y, et al. (2005). "First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase". J. Biochem. 135 (3): 279–83.
doi:
10.1093/jb/mvh033.
PMID15113825.
Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of
prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human
megakaryocytes.[8]
Kanaoka Y, Urade Y (2004). "Hematopoietic prostaglandin D synthase". Prostaglandins Leukot. Essent. Fatty Acids. 69 (2–3): 163–7.
doi:
10.1016/S0952-3278(03)00077-2.
PMID12895599.
Suzuki T, Watanabe K, Kanaoka Y, et al. (1998). "Induction of hematopoietic prostaglandin D synthase in human megakaryocytic cells by phorbol ester". Biochem. Biophys. Res. Commun. 241 (2): 288–93.
doi:
10.1006/bbrc.1997.7803.
PMID9425264.
Sui D, Wilson JE (2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase". Arch. Biochem. Biophys. 382 (2): 262–74.
doi:
10.1006/abbi.2000.2019.
PMID11068878.
Noguchi E, Shibasaki M, Kamioka M, et al. (2002). "New polymorphisms of haematopoietic prostaglandin D synthase and human prostanoid DP receptor genes". Clin. Exp. Allergy. 32 (1): 93–6.
doi:
10.1046/j.0022-0477.2001.01261.x.
PMID12002745.
S2CID24779233.
Inoue T, Irikura D, Okazaki N, et al. (2003). "Mechanism of metal activation of human hematopoietic prostaglandin D synthase". Nat. Struct. Biol. 10 (4): 291–6.
doi:
10.1038/nsb907.
PMID12627223.
S2CID25214344.
Ando M, Murakami Y, Kojima F, et al. (2003). "Retrovirally introduced prostaglandin D2 synthase suppresses lung injury induced by bleomycin". Am. J. Respir. Cell Mol. Biol. 28 (5): 582–91.
doi:
10.1165/rcmb.2002-0162OC.
PMID12707014.
Inoue T, Okano Y, Kado Y, et al. (2005). "First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase". J. Biochem. 135 (3): 279–83.
doi:
10.1093/jb/mvh033.
PMID15113825.