Interferon kappa, also known as IFN-kappa, is a
protein that in humans is encoded by the IFNKgene.[5][6][7]
Function
IFN-kappa is a member of the type I
interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in
keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster.[5]
Ferreira RC, Pan-Hammarström Q, Graham RR, et al. (2010). "Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency". Nat. Genet. 42 (9): 777–80.
doi:
10.1038/ng.644.
PMID20694011.
S2CID205356843.
van Es MA, Veldink JH, Saris CG, et al. (2009). "Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis". Nat. Genet. 41 (10): 1083–7.
doi:
10.1038/ng.442.
PMID19734901.
S2CID8659710.
Interferon kappa, also known as IFN-kappa, is a
protein that in humans is encoded by the IFNKgene.[5][6][7]
Function
IFN-kappa is a member of the type I
interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in
keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster.[5]
Ferreira RC, Pan-Hammarström Q, Graham RR, et al. (2010). "Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency". Nat. Genet. 42 (9): 777–80.
doi:
10.1038/ng.644.
PMID20694011.
S2CID205356843.
van Es MA, Veldink JH, Saris CG, et al. (2009). "Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis". Nat. Genet. 41 (10): 1083–7.
doi:
10.1038/ng.442.
PMID19734901.
S2CID8659710.