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Estradiol undecylate /
norethisterone enanthate
Estradiol undecylate (top) and
norethisterone enanthate (bottom)
Combination of
Estradiol undecylate Estrogen
Norethisterone enanthate Progestogen
Clinical data
Other namesEU/NETE
Routes of
administration		 Intramuscular injection

Estradiol undecylate/norethisterone enanthate (EU/NETE) is a combination medication of estradiol undecylate (EU), an estrogen, and norethisterone enanthate (NETE), a progestin, which was developed by Schering for potential use as a combined injectable contraceptive in women but was ultimately never marketed. [1] [2] [3] [4] [5] [6] It contained 5 to 10 mg EU and 50 to 70 mg NETE in oil solution and was intended for use by intramuscular injection at regular intervals. [1] [2] [3] [4] [5] [6] Although never commercialized, EU/NETE was found to be effective and well tolerated. [1] [2] [3] [4] [5] [6]

See also

References

  1. ^ a b c Karim M, el-Mahgoub S (July 1971). "Conception control by cyclic injections of norethisterone enanthate and estradiol unducelate". Am. J. Obstet. Gynecol. 110 (5): 740–2. doi: 10.1016/0002-9378(71)90268-7. PMID  5563241.
  2. ^ a b c Toppozada MK (1994). "Existing once-a-month combined injectable contraceptives". Contraception. 49 (4): 293–301. doi: 10.1016/0010-7824(94)90029-9. PMID  8013216.
  3. ^ a b c Mokhtar K. Toppozada (1983). "Monthly Injectable Contraceptives". In Alfredo Goldsmith; Mokhtar Toppozada (eds.). Long-Acting Contraception. pp. 93–103. OCLC  35018604.
  4. ^ a b c Toppozada M (June 1977). "The clinical use of monthly injectable contraceptive preparations". Obstet Gynecol Surv. 32 (6): 335–47. doi: 10.1097/00006254-197706000-00001. PMID  865726.
  5. ^ a b c Dr. S. S. Kadam (July 2007). Principles of Medicinal Chemistry Volume 2. Pragati Books Pvt. Ltd. pp. 381–. ISBN  978-81-85790-03-9.
  6. ^ a b c Newton JR, D'arcangues C, Hall PE (1994). "A review of "once-a-month" combined injectable contraceptives". J Obstet Gynaecol (Lahore). 4 (Suppl 1): S1–34. doi: 10.3109/01443619409027641. PMID  12290848.



Stub icon

This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.

Retrieved from " https://en.wikipedia.org/?title=Estradiol_undecylate/norethisterone_enanthate&oldid=1216975314"
From Wikipedia, the free encyclopedia
Estradiol undecylate /
norethisterone enanthate
Estradiol undecylate (top) and
norethisterone enanthate (bottom)
Combination of
Estradiol undecylate Estrogen
Norethisterone enanthate Progestogen
Clinical data
Other namesEU/NETE
Routes of
administration		 Intramuscular injection

Estradiol undecylate/norethisterone enanthate (EU/NETE) is a combination medication of estradiol undecylate (EU), an estrogen, and norethisterone enanthate (NETE), a progestin, which was developed by Schering for potential use as a combined injectable contraceptive in women but was ultimately never marketed. [1] [2] [3] [4] [5] [6] It contained 5 to 10 mg EU and 50 to 70 mg NETE in oil solution and was intended for use by intramuscular injection at regular intervals. [1] [2] [3] [4] [5] [6] Although never commercialized, EU/NETE was found to be effective and well tolerated. [1] [2] [3] [4] [5] [6]

See also

References

  1. ^ a b c Karim M, el-Mahgoub S (July 1971). "Conception control by cyclic injections of norethisterone enanthate and estradiol unducelate". Am. J. Obstet. Gynecol. 110 (5): 740–2. doi: 10.1016/0002-9378(71)90268-7. PMID  5563241.
  2. ^ a b c Toppozada MK (1994). "Existing once-a-month combined injectable contraceptives". Contraception. 49 (4): 293–301. doi: 10.1016/0010-7824(94)90029-9. PMID  8013216.
  3. ^ a b c Mokhtar K. Toppozada (1983). "Monthly Injectable Contraceptives". In Alfredo Goldsmith; Mokhtar Toppozada (eds.). Long-Acting Contraception. pp. 93–103. OCLC  35018604.
  4. ^ a b c Toppozada M (June 1977). "The clinical use of monthly injectable contraceptive preparations". Obstet Gynecol Surv. 32 (6): 335–47. doi: 10.1097/00006254-197706000-00001. PMID  865726.
  5. ^ a b c Dr. S. S. Kadam (July 2007). Principles of Medicinal Chemistry Volume 2. Pragati Books Pvt. Ltd. pp. 381–. ISBN  978-81-85790-03-9.
  6. ^ a b c Newton JR, D'arcangues C, Hall PE (1994). "A review of "once-a-month" combined injectable contraceptives". J Obstet Gynaecol (Lahore). 4 (Suppl 1): S1–34. doi: 10.3109/01443619409027641. PMID  12290848.



Stub icon

This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.

Retrieved from " https://en.wikipedia.org/?title=Estradiol_undecylate/norethisterone_enanthate&oldid=1216975314"

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