| acetyl-CoA hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.1 | ||||||||
| CAS no. | 9027-54-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme acetyl-CoA hydrolase (EC 3.1.2.1) catalyzes the reaction
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is CoA thiol esterase. This enzyme participates in pyruvate metabolism.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2H4U.
- Acetyl-CoA synthetase and ACSS2, enzymes that perform the reverse reaction using ATP
- Gergely J, Hele P, Ramakrishnan CV (1952). "Succinyl and acetyl coenzyme A deacylases". J. Biol. Chem. 198 (1): 323–334. PMID 12999747.[ permanent dead link]
| acetyl-CoA hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.1 | ||||||||
| CAS no. | 9027-54-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme acetyl-CoA hydrolase (EC 3.1.2.1) catalyzes the reaction
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is CoA thiol esterase. This enzyme participates in pyruvate metabolism.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2H4U.
- Acetyl-CoA synthetase and ACSS2, enzymes that perform the reverse reaction using ATP
- Gergely J, Hele P, Ramakrishnan CV (1952). "Succinyl and acetyl coenzyme A deacylases". J. Biol. Chem. 198 (1): 323–334. PMID 12999747.[ permanent dead link]