This is an archive of past discussions. Do not edit the contents of this page. If you wish to start a new discussion or revive an old one, please do so on the current talk page. |
Archive 1 | Archive 2 | Archive 3 | Archive 4 | Archive 5 |
The Original Barnstar | ||
For the incredible amount of work you've done on transcription factor articles and Template:Transcription factors! -- Forluvoft ( talk) 23:18, 2 January 2008 (UTC) |
Thanks Forluvoft! I would also like to thank you for creating many of the pages that I linked together with the Template:Transcription factors navagation box! I also thank User:Arcadian for providing a strong foundation on which to build on. Boghog2 ( talk) 08:36, 3 January 2008 (UTC)
As you wanted, I've moved ERCC2 gene to ERCC2. Regards, Angus McLellan (Talk) 18:09, 6 January 2008 (UTC)
Hi Boghog2,
I just edited RING finger domain. Please let me know if you need wikified files for any protein families. I can send them to you or include information myself. Thank you. Biophys ( talk) 00:11, 19 January 2008 (UTC)
The Tireless Contributor Barnstar | ||
For your work in organizing and linking together hundreds of gene articles otherwise disconnected. Banus ( talk) 09:44, 25 January 2008 (UTC) |
Thank you for not thinking of me as that vandal wrote! Mikael Häggström ( talk) 06:05, 26 January 2008 (UTC)
I just wanted to say I thought that was a novel idea and I hope it catches on in the other scientific wikipages that can be a little über-technical. Rhetth ( talk) 23:32, 14 February 2008 (UTC)
Hi! I noticed you added RE1-Silencing Transcription factor to REST, turning it into a disambiguation page. But Rest already seems to be an established disambiguation page for that word, including for acronyms and abbreviations, so I took the initiative of moving RE1-Silencing Transcription factor there ( Representational State Transfer, which REST had previously redirected to, was already listed there), and changing REST to point to Rest rather than Representational State Transfer. I hope you don't mind! Best wishes, Duncan MacKenzie ( talk) 19:27, 18 February 2008 (UTC).
Hi Boghog, care to chime in on ideas for Google Summer of Code 2008 (see also the talk page there for context)? Originally I thought I'd only list PBB improvements, but it might also make sense to broaden it to any bio-related computer-assisted projects. Perhaps something relating to the protein-boxes you've been working so hard on? Ideas on this or any other topic are welcome... Cheers, AndrewGNF ( talk) 17:53, 26 February 2008 (UTC)
... excellent work on the references! Thanks for doing that - it's way better - Alison ❤ 06:09, 5 March 2008 (UTC)
Hi.
Nice formulae! I would appreciate it, if someone could add essential 3D structures. Some time ago someone explained the whole procedure and it seems to be very easy. The gratis online service
CORINA, developed by the german professor
Gasteiger, stands out for user-friendliness, speed and an amazing conformational accuracy. One must admit that the provided conformation may have the appearance characteristic of crystal structures, and in a context of receptor-ligand binding this may be a weakpoint that has to be weighed in each single case. I could cross-check the drawings with an old hyperchem version.
My idea and my advice is to make
SAR principles directly comprehensable, instead of huddling together an inflation of poor 3D drawings, from which the layman can't grasp any interrelationship. This requires a basic knowledge of the
pharmacophore by the drawer or at least a reviewer, and is expressed by an accurate alignment of structures overlapping the entries. I am willing to assist here and to give further explanations. —Preceding
unsigned comment added by
87.183.95.239 (
talk)
15:59, 13 March 2008 (UTC)
Thanks for your reply.
wp hates high-quality and loves trash structures. To thoroughly elucidate the provenience, the flow of genesis of structures would be the crucial point, and to sufficiently explain (in the text) minor deficiencies, that may possibly reside. Interestingly, I myself was doing research in that lab (at that time with those fellows!) where the D5 ligand was synthesized. But, seemingly, I can't help here.
87.183.104.5 (
talk) —Preceding
comment was added at
23:12, 14 March 2008 (UTC)
Good catch... slightly embarrassed... ;) AndrewGNF ( talk) 17:07, 7 April 2008 (UTC)
Hi Boghog2, Thanks for the corrections on the FPR receptor page. The page is still under development but I have a constant problem with it. After each editing there is a mess on it due to the table on the right. I have tried to fuse the three tables but I could not make it. Could you help me please? (I am working on 'Chemotaxis' related pages, but FPR-receptor page is the first where I have constant problems...) Thank for your help in advance. Best regrds from Kohlasz ( talk) 04:08, 10 April 2008 (UTC)
Hi Boghog2. I agree this page could do with a rewrite but there are other factors you have not considered. See talk page for details. Meodipt ( talk) 09:02, 13 April 2008 (UTC)
I appreciate they're often about both, to some degree or another, but my category analysis identified that they were primarily categorised by (and thus, implicitly, as) genes, so that's why I proposed splitting them on that basis. (To which there seemed to be fairly general agreement.) Looking at a number of the article texts seemed to bear that out, but I realize there's bound to be exceptions. Would it be sufficient to clarify the scope of the stub types so as to expressly include "proteins by chromosome number"? If that's not a useful split for the articles, then they'll have to be "unsorted" back into the proteins in the short term, and sooner or later re-sorted on some other basis, to deal with the stub category size issue. I'd need to know more about what articles are affected before I could comment sensibly on the feasibility of doing so. My bot's not currently sorting these (it was a one-off run), so any chances back should be "stable" for the foreseeable future. Alai ( talk) 14:45, 27 May 2008 (UTC)
Hi there Boghog, I noticed your recent reversion of vandalism on Immune system and thought you might like access to the rollback feature. You may not have to use it much, but it greatly simplifies the reverting process, and I'm confident you wouldn't use it inappropriately. Just follow the above link for information on how to use it, or let me know if you have any doubts. Best, Fvasconcellos ( t· c) 19:48, 5 June 2008 (UTC)
Your tryptophan biosynthesis image has a minor error -- the I-3-GP molecule looks like a phosphonate instead of a phosphate; needs one of those carbons to be an oxygen! Takometer ( talk) 21:01, 7 June 2008 (UTC)
I like all the work you've done 'round here. Articles that you tackle are consistently much better after you wrestle with the content.
If you have any future interest in adminship, let me know. I'd be happy to suggest a few things and offer a nomination. — Scien tizzle 20:33, 8 July 2008 (UTC)
Glad to see some science voices on slashdot, and had a chuckle when I saw your name. (Been watching there, but not really participating...) Keep up the evangelism! Cheers, AndrewGNF ( talk) 21:03, 10 July 2008 (UTC)
Thank you for uploading Image:Hsp90 schematic 2cg9.png. However, it currently is missing information on its copyright status. Wikipedia takes copyright very seriously. It may be deleted soon, unless we can determine the license and the source of the image. If you know this information, then you can add a copyright tag to the image description page.
If you have any questions, please feel free to ask them at the media copyright questions page. Thanks again for your cooperation. Sdrtirs ( talk) 02:33, 12 July 2008 (UTC)
Thank you for uploading images/media to Wikipedia! There is, however, another Wikimedia Foundation project called Wikimedia Commons, a central media repository for all free media. In future, please upload media there instead (see m:Help:Unified login). That way, all of the other language Wikipedias can use them too, as well as our many sister projects. This will also allow our visitors to search for, view and use our media in one central location. If you wish to move previous uploads to Commons, see Wikipedia:Moving images to the Commons (you may view images you have previously uploaded by going to your user contributions on the left and choosing the 'image' namespace from the drop down box). Please note that non-free content, such as images claimed as fair use, cannot be uploaded to the Wikimedia Commons. Help us spread the word about Commons by informing other users, and please continue uploading!-- O sama K 22:56, 13 July 2008 (UTC)
Hi Boghog2! I'm writing to ask you if I can move pictures you created for biochemistry (and for Tyrosine page above all) to Wikimedia Commons. I'd like to use them in Wikipedia sister projects (Italian Wikipedia). I'm not very experienced at Wikipedia rules, so I'm here asking. Thank you! -- Damiano ( talk) 13:38, 21 July 2008 (UTC)
Hi, i read your edit summary on the GABAA_receptor article. As far as I know the alpha4 and alpha6 sites are still benzodiazepine containing subunits even if diazepam and the other benzodiazepine drugs don't bind to them. There are other benzodiazepine ligands which bind to the benzodiazepine alpha4 and alpha6 subunits, eg flumazenil I am almost certain binds to them as a benzodiazepine receptor antagonist. You are correct that the phrase "BZ-sensitive GABAA receptors" is used in the reference but it is used only one time and it is used in quotation marks. In the parts where they recommend adopting certain terms of description and casting aside others etc, this term is not used, therefore I feel to say that they recommend adopting this new term is a misrepresentation of what they said because they never recommended adopting it. Especially as they only put it in quotes would imply that they were only using it as a description and not intending it to become the new official description.-- Literaturegeek | T@1k? 07:11, 26 July 2008 (UTC)
When benzodiazepines were invented, the benzodiazepine receptor was unknown and I think even the GABA receptor was unknown as well. When I believe in the 1970's the benzo receptor was discovered the receptors got their name (from the drug class benzodiazepines). The drug came first, then the discovery of the receptors (a lot later) and the study of the various sub types of benzo receptors has only really been during the past decade or two, but like I say alpha4 and alpha6 are insensitive to the benzodiazepine drug, this doesn't mean they aren't benzo receptors. Anyway if I am incorrect in anything that I have said feel free to correct me. I am always willing to be proved wrong and learn from my mistakes. Sorry for taking up your time boghog.-- Literaturegeek | T@1k? 07:29, 26 July 2008 (UTC)
No problems Boghog. I see you have improved on the article even further, good job. It is reading much better now with both of our edits. I hope that you have a good day.-- Literaturegeek | T@1k? 21:16, 26 July 2008 (UTC)
Oh by the way, you wouldn't have any knowledge on how alcohol affects the GABAa receptor complex? Like what subunits it binds to? I know that it modulates the chloride ion channel similar to the barbs and benzos but am rusty on knowledge about ethanol's pharmacology. It might be worth some time adding sections on how barbs, neurosteroids and ethanol modulates the GABAa receptor complex to the GABAA receptor wiki article.-- Literaturegeek | T@1k? 21:19, 26 July 2008 (UTC)
{{
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help)CS1 maint: multiple names: authors list (
link)) have speculated that the ethanol binding site overlaps with the azido group of Ro15-4513 when Ro15-4513 is bound to the GABAA receptor complex. I agree it would be useful to add more detail about the other allosteric binding sites on the GABAA receptor complex. When I find some time, I will work on this. Cheers.
Boghog2 (
talk)
12:33, 27 July 2008 (UTC)Thanks for the information. That is interesting because benzos don't bind to that subunit. There must surely be more subunits orr receptor systems that ethanol binds to? It is such a powerful drug you would think that it would bind to a multitude of receptor complexes. I am thinking of trying to get full text of this paper which I think would answer a lot of my questions. [1] If or when I get the full text I will be able to help you write up the alcohol part of the GABAa receptor article.-- Literaturegeek | T@1k? 22:26, 28 July 2008 (UTC)
Locus | Serotype |
HLA-DRB3 | HLA-DR52 |
HLA-DRB4 | HLA-DR53 |
HLA-DRB5 | HLA-DR51 |
I want to thank you for your help on the HLA-DRA page, I recovered the old converted protein box for HLA-DR, but since you have created all the gene pages it would be redundant, what I did was cut out all the outside links and created wiki-links to the pages you created. This is the best of all worlds now because it is remarkable shorter but conveys the essential information. Let me tell you what my goal was on the subpages (HLA-DQ2 as an example). The illustration on the HLA-{locus} page is fine, but if we have 3D images of the various HLA-DQ, if you could get a list of names of these structures I can tell you what pages they best go to, that way we can limit the number of links, and spread them around to the appropriate pages. For example, the image of the DRB1 page is DRB1*0101, that image goes on the DR1 page. Check the tables in the DR page, you will find that DRB3, 4, and 5 may be best combined with DR52, 53, 51 respectively. Since the gene named pages will hold future priority, I think it might be best that the DR5x pages be combined into the HLA-DRBx pages. PB666 yap 03:42, 28 July 2008 (UTC)
I am not sure what HLA-DQA2, HLA-DQB2 actually do, there is no serology associated with these and no alleles published currently. The literature on HLA-DQB3 gives a strong implication that it is a psuedogene. PB666 yap 11:58, 3 August 2008 (UTC)
Thanks for fixing my mess --- looks great! —Preceding unsigned comment added by 99.231.222.224 ( talk) 03:42, 4 August 2008 (UTC)
Hi there. When you made this page about Di-p-tolylguanidine were you thinking of Di-o-tolylguanidine which is the sigma ligand the reference refers to? The para- analogue does exist as well but I'm unsure if they have the same activity. Meodipt ( talk) 03:45, 10 August 2008 (UTC)
dear BogHog2, I have added external links appropriate and relevant to the Gene. This is not spamming, advertising or an inappropriate link. Those are governmental links about that specific gene and the reader will gain much more information through clicking on those Genes than reading from what the ProteinBoxBot has created. That Bot is getting all information from Entrez. Wouldn't that be considered as spamming also? Aminoacid91 ( talk) 21:05, 12 August 2008 (UTC)
Hi Boghog2,
I apologize in advance if I am screwing up this page, have never tried to contact someone via wikipedia before!
I am working on a show for Spike TV, would like to license your GW1516 molecule illustration, and am willing to pay you $100 for the license.
Could you please contact me ASAP so that we may move forward.
Sincerely,
David Ballard MANSWERS Spike TV (323) 459-9857 ballardmedia@yahoo.com
64.60.86.106 ( talk) 18:45, 21 August 2008 (UTC)
Thanx for editing the reelin page! I'm plannning a major expansion, any help is appreciated. Maybe later 'll try to make it a "Good article".. Best regards, -- CopperKettle ( talk) 15:54, 22 August 2008 (UTC)
An article that you have been involved in editing, C9orf3, has been listed for deletion. If you are interested in the deletion discussion, please participate by adding your comments at Wikipedia:Articles for deletion/C9orf3. Thank you. Do you want to opt out of receiving this notice? Dpmuk ( talk) 21:38, 1 September 2008 (UTC)
Oh, sorry. I'm in #cvn-wp-en and Miszabot founded out a large removal, Be careful what you do with edits, or put a notice on the article to let everyone know of the merger. Thanks Techman224 ( talk) 20:27, 3 September 2008 (UTC)
I thought you might be interested to know that I have posted a longer reason as to why I think this gene should be deleted which I did not, through niavity, include in my original arguement. Dpmuk ( talk) 11:11, 4 September 2008 (UTC)
A tag has been placed on Image:Phe Tyr.png requesting that it be speedily deleted from Wikipedia. This has been done under section I8 of the criteria for speedy deletion, because it is available as a bit-for-bit identical copy on the Wikimedia Commons under the same name, or all references to the image on Wikipedia have been updated to point to the title used at Commons.
If you think that this notice was placed here in error, you may contest the deletion by adding {{
hangon}}
to the top of
the page that has been nominated for deletion (just below the existing speedy deletion or "db" tag), coupled with adding a note on [[ Talk:Image:Phe Tyr.png|the talk page]] explaining your position, but be aware that once tagged for speedy deletion, if the article meets the criterion it may be deleted without delay. Please do not remove the speedy deletion tag yourself, but don't hesitate to add information to the article that would would render it more in conformance with Wikipedia's policies and guidelines. Lastly, please note that if the article does get deleted, you can contact
one of these admins to request that a copy be emailed to you.
JaGa
talk
00:10, 17 September 2008 (UTC)
Hello Mr Boghog2, I've written an article recently on the guanine nucleotide exchange factor SGEF, but not sure how to construct an accompanying protein box. I'd be most grateful if you could either make one or send me a quick guide of how to do it so that i can do it myself in the future. The Entrez gene ID for this protein is 26084. Many thanks. George Damoulakis ( talk) 17:36(GMT), 9 October 2008
Thanks Dr/Mr (?) Boghog2, for significantly improving the Lacritin article. Is there a way to replace Image:PBB GE LACRT gnf1h01120 at tn.png with more representative display of lacritin expression? I list several in the article. The Unigene image is preferred. Glaurie ( talk) 7:39 am, 14 October 2008
Hi Boghog2. Why is there no page for CHRNA8? I've been following the development of the subtype-selective nACh ligands with some interest and just noticed that there is no page for the α8 subunit. Not that its particularly notable at present, but I expect all of these subtypes will have selective ligands in the near future, and it seemed like an odd omission. Meodipt ( talk) 22:32, 17 October 2008 (UTC) Seems to be expressed mainly on GABAergic neurons, and with a similar but not identical distribution to the better studied α7 subunit (see PMID 10678774, PMID 11593308, PMID 15972832) Meodipt ( talk) 22:59, 17 October 2008 (UTC)
{{
cite journal}}
: Unknown parameter |month=
ignored (
help){{
cite journal}}
: Unknown parameter |month=
ignored (
help)CS1 maint: multiple names: authors list (
link){{
cite journal}}
: Cite has empty unknown parameter: |month=
(
help)CS1 maint: multiple names: authors list (
link) CS1 maint: unflagged free DOI (
link)The PDB and PDB3 templates don't seem like they comply with Wikipedia's standard practice regarding external links. Per guidelines, external links shouldn't be used in the body of an article. The reason I bring this up is your recent reversion of one of my edits to restriction enzyme (see diff), in which you restored an external link via the PDB template. Such external linking is absent throughout all of the relevant featured articles in biology (e.g. DNA repair, exosome complex, RNA interference), the recently promoted FA Rosetta@home and all of the protein-related good articles I looked through (e.g. Arp2/3 complex, Protein). Given that, shouldn't the PDB and PDB3 templates be deprecated? The PDB2 template seems like a viable alternative.
Also, given the MOS:IMAGES recommendation against forced sizing when images display well enough with the 180px default, shouldn't the 260px forced sizing you also restored in the 1qps image be removed as well? Cheers, Emw2012 ( talk) 22:10, 21 October 2008 (UTC)
Thank you for helping out with that. I just was doing Random Article Improvement. -- ₪ Amused Repose Converse! 22:29, 23 October 2008 (UTC)
(about the article KCNC1 Dear friend. You have "removed redundant URL from citation that contains a DOI, both point to the same page therefore no reason to include both, also DOIs are preferable since they are guaranteed not to change". However, I think that you did not take into account the all aspects of the issue. For example, article #7 (Rudy et al) also has a DOI. But this article has no open access, so providing the link with a url is senseless. But the article #4 (Gutman et al) has the open access. So, it is quite reasonable to provide this link also with url to underline the possibility for each user of Wikipedia to get the full text of the article using the link.-- Yuriy Kolodin ( talk) 13:49, 26 October 2008 (UTC)
Good edits. Carry on. -- Una Smith ( talk) 21:55, 27 October 2008 (UTC)
Darned nice of you. S B H arris 21:57, 28 October 2008 (UTC)
Your picture of the A2A receptor looks just great, I therefore wanted to ask you if you could the same for the TRPV1 channel. The PDB model is here: http://cbsm.utalca.cl/cecs/files/pdb/trpv1_pip2.zip, the reference is here: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1891241. Thanks Panoramix303 ( talk) 17:33, 31 October 2008 (UTC)
That article is unfortunately wrong. I know biocarta.com has the wrong transporter too. See Talk:Glutamate_aspartate_transporter. -- Ayacop ( talk) 16:43, 11 November 2008 (UTC)
Thanks for creating the LAG-3 article. You have put in a lot of references but none of them are in-line, which means I cannot tell what refers to what? -- 92.3.124.93 ( talk) 21:40, 14 November 2008 (UTC)
A tag has been placed on Image:L-tryptophan.png requesting that it be speedily deleted from Wikipedia. This has been done under section I8 of the criteria for speedy deletion, because it is available as a bit-for-bit identical copy on the Wikimedia Commons under the same name, or all references to the image on Wikipedia have been updated to point to the title used at Commons.
If you think that this notice was placed here in error, you may contest the deletion by adding {{
hangon}}
to the top of
the page that has been nominated for deletion (just below the existing speedy deletion or "db" tag), coupled with adding a note on [[ Talk:Image:L-tryptophan.png|the talk page]] explaining your position, but be aware that once tagged for speedy deletion, if the article meets the criterion it may be deleted without delay. Please do not remove the speedy deletion tag yourself, but don't hesitate to add information to the article that would would render it more in conformance with Wikipedia's policies and guidelines. Lastly, please note that if the article does get deleted, you can contact
one of these admins to request that a copy be emailed to you.
JaGa
talk
08:18, 16 November 2008 (UTC)
Thanks for noticing my image----it is for a specific protein but does fit in the same species as 7-dehydrocholesterol reductase which is why I added the image in the first place. I put it back on the page because this is for a biochem test and I need something up on that partcular page until she grades it. I will also be adding other comments and will remark on the fact that the image is realted but not exact. Thanks for your help. Whitek94 ( talk) 18:41, 18 November 2008 (UTC)
Hi Boghog2. Should these two pages be merged? GPR172A and GHB receptor or is there more than one GHB receptor? Also is GPR172A the same as GPR172? Meodipt ( talk) 11:44, 19 November 2008 (UTC)
Hi Boghog2. Do you know anything about this receptor? I can't find much but maybe it is one of those unidentified orphan GPCRs...there is some reasonable evidence for its existence here and a few selective ligands have been identified ( PMID 16719773 PMID 15246090) but then this paper ( PMID 15178356) says the apparent epsilon opioid receptor effects seem to be mediated through the classic opioid receptors instead so its a bit of a puzzle. Meodipt ( talk) 01:55, 1 December 2008 (UTC)
{{
cite web}}
: Cite has empty unknown parameter: |coauthors=
(
help)Hello Boghog and thanks for the editing and formating on the cugbp1 page. I have been wondering why the page is back to a minimal content page like the one originally created by the bot ?
This modification does not appear in the history.
OK, everything is back.yann —Preceding unsigned comment added by Yann.audic ( talk • contribs) 14:30, 4 December 2008 (UTC)
yann —Preceding unsigned comment added by Yann.audic ( talk • contribs) 14:26, 4 December 2008 (UTC)
Thanks for reviewing the changes I made. The citation you put in (Phospholipid scramblases: An overview) is basically what I used. I could go back an insert individual references. But I thought just having it there would be ok. What do you think? Artephius ( talk) 16:24, 5 December 2008 (UTC)
I'll get on that then. Artephius ( talk) 21:03, 5 December 2008 (UTC)
Hi Boghog, thank you for help. I am almost finished with the article, just remains som re-writing and citations about histology and determination in tissue extracts. Then I plan to continue with some other tumour marker.
By the way, on the discussion page, there is a remark about the article being an unimportnat stub. I do not know exactly the definition of a stub, but the article was not a stub when I started adding citations last week, and the enzyme is definitely not unimportant, as it is the deciding port of entry of several drugs and also importnat in clinical chemistry. Should this remark on the discussion page be modified? Lave ( talk) 07:25, 29 November 2008 (UTC)
Hejsan! Somebody is helping you to edit Tyrosine aminotransferase, but who is that person really and where do these images come from? I asked a question at commons:Commons:Village pump#Strange uploads. -- LA2 ( talk) 07:25, 11 December 2008 (UTC)
Though we rarely talk directly, I wanted to make sure you know how much I appreciate the wonderful work you do, and and how much I enjoy our silent collaboration. -- Arcadian ( talk) 01:27, 2 December 2008 (UTC)
I'd also like to thank you for the citation advice. I've got a lot to learn. Abe ( talk) 20:07, 14 December 2008 (UTC)
I hope that you have a happy Christmas and have a Happy New Year Bog. Try not to modulate those alpha subunits too much on New Years eve night!:=) LOL-- Literaturegeek | T@1k? 21:06, 22 December 2008 (UTC)
Hello, Boghog I noticed that you edited a link on the CLCNKB article back in July; the Homologene link is retired and I was trying to replace it with a link to Gene ( http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1188&ordinalpos=1&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum) but I don't know the code. Can you help? doctorwolfie ( talk) 11:18, 23 December 2008 (UTC)
Boghog: Gott Nytt År!! Allt gott under 2009! Lave ( talk) 12:28, 30 December 2008 (UTC)
Boghog2 thanx for welcoming me and the great advice too. i am part of a large group developing a grant application to the national inst of health to set up a web site to assist the community in learning about research on cleft lip and palate. we wanted to use the gene wikis as a common, easily accessible format to curate up to date information on genes especially relevant to cleft lip so a few of us will be trying to edit perhaps 20 or so gene entries. but we realize we are a specialized community so dont want to offend anyone. any advice or central resources we could access for this kind of work. thanx a lot we really love wikipedia and gene wikis especially. i will try to sign off the correct way i hope i get it right Jcmurray24 ( talk) 23:08, 30 December 2008 (UTC)
This is an archive of past discussions. Do not edit the contents of this page. If you wish to start a new discussion or revive an old one, please do so on the current talk page. |
Archive 1 | Archive 2 | Archive 3 | Archive 4 | Archive 5 |
The Original Barnstar | ||
For the incredible amount of work you've done on transcription factor articles and Template:Transcription factors! -- Forluvoft ( talk) 23:18, 2 January 2008 (UTC) |
Thanks Forluvoft! I would also like to thank you for creating many of the pages that I linked together with the Template:Transcription factors navagation box! I also thank User:Arcadian for providing a strong foundation on which to build on. Boghog2 ( talk) 08:36, 3 January 2008 (UTC)
As you wanted, I've moved ERCC2 gene to ERCC2. Regards, Angus McLellan (Talk) 18:09, 6 January 2008 (UTC)
Hi Boghog2,
I just edited RING finger domain. Please let me know if you need wikified files for any protein families. I can send them to you or include information myself. Thank you. Biophys ( talk) 00:11, 19 January 2008 (UTC)
The Tireless Contributor Barnstar | ||
For your work in organizing and linking together hundreds of gene articles otherwise disconnected. Banus ( talk) 09:44, 25 January 2008 (UTC) |
Thank you for not thinking of me as that vandal wrote! Mikael Häggström ( talk) 06:05, 26 January 2008 (UTC)
I just wanted to say I thought that was a novel idea and I hope it catches on in the other scientific wikipages that can be a little über-technical. Rhetth ( talk) 23:32, 14 February 2008 (UTC)
Hi! I noticed you added RE1-Silencing Transcription factor to REST, turning it into a disambiguation page. But Rest already seems to be an established disambiguation page for that word, including for acronyms and abbreviations, so I took the initiative of moving RE1-Silencing Transcription factor there ( Representational State Transfer, which REST had previously redirected to, was already listed there), and changing REST to point to Rest rather than Representational State Transfer. I hope you don't mind! Best wishes, Duncan MacKenzie ( talk) 19:27, 18 February 2008 (UTC).
Hi Boghog, care to chime in on ideas for Google Summer of Code 2008 (see also the talk page there for context)? Originally I thought I'd only list PBB improvements, but it might also make sense to broaden it to any bio-related computer-assisted projects. Perhaps something relating to the protein-boxes you've been working so hard on? Ideas on this or any other topic are welcome... Cheers, AndrewGNF ( talk) 17:53, 26 February 2008 (UTC)
... excellent work on the references! Thanks for doing that - it's way better - Alison ❤ 06:09, 5 March 2008 (UTC)
Hi.
Nice formulae! I would appreciate it, if someone could add essential 3D structures. Some time ago someone explained the whole procedure and it seems to be very easy. The gratis online service
CORINA, developed by the german professor
Gasteiger, stands out for user-friendliness, speed and an amazing conformational accuracy. One must admit that the provided conformation may have the appearance characteristic of crystal structures, and in a context of receptor-ligand binding this may be a weakpoint that has to be weighed in each single case. I could cross-check the drawings with an old hyperchem version.
My idea and my advice is to make
SAR principles directly comprehensable, instead of huddling together an inflation of poor 3D drawings, from which the layman can't grasp any interrelationship. This requires a basic knowledge of the
pharmacophore by the drawer or at least a reviewer, and is expressed by an accurate alignment of structures overlapping the entries. I am willing to assist here and to give further explanations. —Preceding
unsigned comment added by
87.183.95.239 (
talk)
15:59, 13 March 2008 (UTC)
Thanks for your reply.
wp hates high-quality and loves trash structures. To thoroughly elucidate the provenience, the flow of genesis of structures would be the crucial point, and to sufficiently explain (in the text) minor deficiencies, that may possibly reside. Interestingly, I myself was doing research in that lab (at that time with those fellows!) where the D5 ligand was synthesized. But, seemingly, I can't help here.
87.183.104.5 (
talk) —Preceding
comment was added at
23:12, 14 March 2008 (UTC)
Good catch... slightly embarrassed... ;) AndrewGNF ( talk) 17:07, 7 April 2008 (UTC)
Hi Boghog2, Thanks for the corrections on the FPR receptor page. The page is still under development but I have a constant problem with it. After each editing there is a mess on it due to the table on the right. I have tried to fuse the three tables but I could not make it. Could you help me please? (I am working on 'Chemotaxis' related pages, but FPR-receptor page is the first where I have constant problems...) Thank for your help in advance. Best regrds from Kohlasz ( talk) 04:08, 10 April 2008 (UTC)
Hi Boghog2. I agree this page could do with a rewrite but there are other factors you have not considered. See talk page for details. Meodipt ( talk) 09:02, 13 April 2008 (UTC)
I appreciate they're often about both, to some degree or another, but my category analysis identified that they were primarily categorised by (and thus, implicitly, as) genes, so that's why I proposed splitting them on that basis. (To which there seemed to be fairly general agreement.) Looking at a number of the article texts seemed to bear that out, but I realize there's bound to be exceptions. Would it be sufficient to clarify the scope of the stub types so as to expressly include "proteins by chromosome number"? If that's not a useful split for the articles, then they'll have to be "unsorted" back into the proteins in the short term, and sooner or later re-sorted on some other basis, to deal with the stub category size issue. I'd need to know more about what articles are affected before I could comment sensibly on the feasibility of doing so. My bot's not currently sorting these (it was a one-off run), so any chances back should be "stable" for the foreseeable future. Alai ( talk) 14:45, 27 May 2008 (UTC)
Hi there Boghog, I noticed your recent reversion of vandalism on Immune system and thought you might like access to the rollback feature. You may not have to use it much, but it greatly simplifies the reverting process, and I'm confident you wouldn't use it inappropriately. Just follow the above link for information on how to use it, or let me know if you have any doubts. Best, Fvasconcellos ( t· c) 19:48, 5 June 2008 (UTC)
Your tryptophan biosynthesis image has a minor error -- the I-3-GP molecule looks like a phosphonate instead of a phosphate; needs one of those carbons to be an oxygen! Takometer ( talk) 21:01, 7 June 2008 (UTC)
I like all the work you've done 'round here. Articles that you tackle are consistently much better after you wrestle with the content.
If you have any future interest in adminship, let me know. I'd be happy to suggest a few things and offer a nomination. — Scien tizzle 20:33, 8 July 2008 (UTC)
Glad to see some science voices on slashdot, and had a chuckle when I saw your name. (Been watching there, but not really participating...) Keep up the evangelism! Cheers, AndrewGNF ( talk) 21:03, 10 July 2008 (UTC)
Thank you for uploading Image:Hsp90 schematic 2cg9.png. However, it currently is missing information on its copyright status. Wikipedia takes copyright very seriously. It may be deleted soon, unless we can determine the license and the source of the image. If you know this information, then you can add a copyright tag to the image description page.
If you have any questions, please feel free to ask them at the media copyright questions page. Thanks again for your cooperation. Sdrtirs ( talk) 02:33, 12 July 2008 (UTC)
Thank you for uploading images/media to Wikipedia! There is, however, another Wikimedia Foundation project called Wikimedia Commons, a central media repository for all free media. In future, please upload media there instead (see m:Help:Unified login). That way, all of the other language Wikipedias can use them too, as well as our many sister projects. This will also allow our visitors to search for, view and use our media in one central location. If you wish to move previous uploads to Commons, see Wikipedia:Moving images to the Commons (you may view images you have previously uploaded by going to your user contributions on the left and choosing the 'image' namespace from the drop down box). Please note that non-free content, such as images claimed as fair use, cannot be uploaded to the Wikimedia Commons. Help us spread the word about Commons by informing other users, and please continue uploading!-- O sama K 22:56, 13 July 2008 (UTC)
Hi Boghog2! I'm writing to ask you if I can move pictures you created for biochemistry (and for Tyrosine page above all) to Wikimedia Commons. I'd like to use them in Wikipedia sister projects (Italian Wikipedia). I'm not very experienced at Wikipedia rules, so I'm here asking. Thank you! -- Damiano ( talk) 13:38, 21 July 2008 (UTC)
Hi, i read your edit summary on the GABAA_receptor article. As far as I know the alpha4 and alpha6 sites are still benzodiazepine containing subunits even if diazepam and the other benzodiazepine drugs don't bind to them. There are other benzodiazepine ligands which bind to the benzodiazepine alpha4 and alpha6 subunits, eg flumazenil I am almost certain binds to them as a benzodiazepine receptor antagonist. You are correct that the phrase "BZ-sensitive GABAA receptors" is used in the reference but it is used only one time and it is used in quotation marks. In the parts where they recommend adopting certain terms of description and casting aside others etc, this term is not used, therefore I feel to say that they recommend adopting this new term is a misrepresentation of what they said because they never recommended adopting it. Especially as they only put it in quotes would imply that they were only using it as a description and not intending it to become the new official description.-- Literaturegeek | T@1k? 07:11, 26 July 2008 (UTC)
When benzodiazepines were invented, the benzodiazepine receptor was unknown and I think even the GABA receptor was unknown as well. When I believe in the 1970's the benzo receptor was discovered the receptors got their name (from the drug class benzodiazepines). The drug came first, then the discovery of the receptors (a lot later) and the study of the various sub types of benzo receptors has only really been during the past decade or two, but like I say alpha4 and alpha6 are insensitive to the benzodiazepine drug, this doesn't mean they aren't benzo receptors. Anyway if I am incorrect in anything that I have said feel free to correct me. I am always willing to be proved wrong and learn from my mistakes. Sorry for taking up your time boghog.-- Literaturegeek | T@1k? 07:29, 26 July 2008 (UTC)
No problems Boghog. I see you have improved on the article even further, good job. It is reading much better now with both of our edits. I hope that you have a good day.-- Literaturegeek | T@1k? 21:16, 26 July 2008 (UTC)
Oh by the way, you wouldn't have any knowledge on how alcohol affects the GABAa receptor complex? Like what subunits it binds to? I know that it modulates the chloride ion channel similar to the barbs and benzos but am rusty on knowledge about ethanol's pharmacology. It might be worth some time adding sections on how barbs, neurosteroids and ethanol modulates the GABAa receptor complex to the GABAA receptor wiki article.-- Literaturegeek | T@1k? 21:19, 26 July 2008 (UTC)
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link)) have speculated that the ethanol binding site overlaps with the azido group of Ro15-4513 when Ro15-4513 is bound to the GABAA receptor complex. I agree it would be useful to add more detail about the other allosteric binding sites on the GABAA receptor complex. When I find some time, I will work on this. Cheers.
Boghog2 (
talk)
12:33, 27 July 2008 (UTC)Thanks for the information. That is interesting because benzos don't bind to that subunit. There must surely be more subunits orr receptor systems that ethanol binds to? It is such a powerful drug you would think that it would bind to a multitude of receptor complexes. I am thinking of trying to get full text of this paper which I think would answer a lot of my questions. [1] If or when I get the full text I will be able to help you write up the alcohol part of the GABAa receptor article.-- Literaturegeek | T@1k? 22:26, 28 July 2008 (UTC)
Locus | Serotype |
HLA-DRB3 | HLA-DR52 |
HLA-DRB4 | HLA-DR53 |
HLA-DRB5 | HLA-DR51 |
I want to thank you for your help on the HLA-DRA page, I recovered the old converted protein box for HLA-DR, but since you have created all the gene pages it would be redundant, what I did was cut out all the outside links and created wiki-links to the pages you created. This is the best of all worlds now because it is remarkable shorter but conveys the essential information. Let me tell you what my goal was on the subpages (HLA-DQ2 as an example). The illustration on the HLA-{locus} page is fine, but if we have 3D images of the various HLA-DQ, if you could get a list of names of these structures I can tell you what pages they best go to, that way we can limit the number of links, and spread them around to the appropriate pages. For example, the image of the DRB1 page is DRB1*0101, that image goes on the DR1 page. Check the tables in the DR page, you will find that DRB3, 4, and 5 may be best combined with DR52, 53, 51 respectively. Since the gene named pages will hold future priority, I think it might be best that the DR5x pages be combined into the HLA-DRBx pages. PB666 yap 03:42, 28 July 2008 (UTC)
I am not sure what HLA-DQA2, HLA-DQB2 actually do, there is no serology associated with these and no alleles published currently. The literature on HLA-DQB3 gives a strong implication that it is a psuedogene. PB666 yap 11:58, 3 August 2008 (UTC)
Thanks for fixing my mess --- looks great! —Preceding unsigned comment added by 99.231.222.224 ( talk) 03:42, 4 August 2008 (UTC)
Hi there. When you made this page about Di-p-tolylguanidine were you thinking of Di-o-tolylguanidine which is the sigma ligand the reference refers to? The para- analogue does exist as well but I'm unsure if they have the same activity. Meodipt ( talk) 03:45, 10 August 2008 (UTC)
dear BogHog2, I have added external links appropriate and relevant to the Gene. This is not spamming, advertising or an inappropriate link. Those are governmental links about that specific gene and the reader will gain much more information through clicking on those Genes than reading from what the ProteinBoxBot has created. That Bot is getting all information from Entrez. Wouldn't that be considered as spamming also? Aminoacid91 ( talk) 21:05, 12 August 2008 (UTC)
Hi Boghog2,
I apologize in advance if I am screwing up this page, have never tried to contact someone via wikipedia before!
I am working on a show for Spike TV, would like to license your GW1516 molecule illustration, and am willing to pay you $100 for the license.
Could you please contact me ASAP so that we may move forward.
Sincerely,
David Ballard MANSWERS Spike TV (323) 459-9857 ballardmedia@yahoo.com
64.60.86.106 ( talk) 18:45, 21 August 2008 (UTC)
Thanx for editing the reelin page! I'm plannning a major expansion, any help is appreciated. Maybe later 'll try to make it a "Good article".. Best regards, -- CopperKettle ( talk) 15:54, 22 August 2008 (UTC)
An article that you have been involved in editing, C9orf3, has been listed for deletion. If you are interested in the deletion discussion, please participate by adding your comments at Wikipedia:Articles for deletion/C9orf3. Thank you. Do you want to opt out of receiving this notice? Dpmuk ( talk) 21:38, 1 September 2008 (UTC)
Oh, sorry. I'm in #cvn-wp-en and Miszabot founded out a large removal, Be careful what you do with edits, or put a notice on the article to let everyone know of the merger. Thanks Techman224 ( talk) 20:27, 3 September 2008 (UTC)
I thought you might be interested to know that I have posted a longer reason as to why I think this gene should be deleted which I did not, through niavity, include in my original arguement. Dpmuk ( talk) 11:11, 4 September 2008 (UTC)
A tag has been placed on Image:Phe Tyr.png requesting that it be speedily deleted from Wikipedia. This has been done under section I8 of the criteria for speedy deletion, because it is available as a bit-for-bit identical copy on the Wikimedia Commons under the same name, or all references to the image on Wikipedia have been updated to point to the title used at Commons.
If you think that this notice was placed here in error, you may contest the deletion by adding {{
hangon}}
to the top of
the page that has been nominated for deletion (just below the existing speedy deletion or "db" tag), coupled with adding a note on [[ Talk:Image:Phe Tyr.png|the talk page]] explaining your position, but be aware that once tagged for speedy deletion, if the article meets the criterion it may be deleted without delay. Please do not remove the speedy deletion tag yourself, but don't hesitate to add information to the article that would would render it more in conformance with Wikipedia's policies and guidelines. Lastly, please note that if the article does get deleted, you can contact
one of these admins to request that a copy be emailed to you.
JaGa
talk
00:10, 17 September 2008 (UTC)
Hello Mr Boghog2, I've written an article recently on the guanine nucleotide exchange factor SGEF, but not sure how to construct an accompanying protein box. I'd be most grateful if you could either make one or send me a quick guide of how to do it so that i can do it myself in the future. The Entrez gene ID for this protein is 26084. Many thanks. George Damoulakis ( talk) 17:36(GMT), 9 October 2008
Thanks Dr/Mr (?) Boghog2, for significantly improving the Lacritin article. Is there a way to replace Image:PBB GE LACRT gnf1h01120 at tn.png with more representative display of lacritin expression? I list several in the article. The Unigene image is preferred. Glaurie ( talk) 7:39 am, 14 October 2008
Hi Boghog2. Why is there no page for CHRNA8? I've been following the development of the subtype-selective nACh ligands with some interest and just noticed that there is no page for the α8 subunit. Not that its particularly notable at present, but I expect all of these subtypes will have selective ligands in the near future, and it seemed like an odd omission. Meodipt ( talk) 22:32, 17 October 2008 (UTC) Seems to be expressed mainly on GABAergic neurons, and with a similar but not identical distribution to the better studied α7 subunit (see PMID 10678774, PMID 11593308, PMID 15972832) Meodipt ( talk) 22:59, 17 October 2008 (UTC)
{{
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help){{
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link){{
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: Cite has empty unknown parameter: |month=
(
help)CS1 maint: multiple names: authors list (
link) CS1 maint: unflagged free DOI (
link)The PDB and PDB3 templates don't seem like they comply with Wikipedia's standard practice regarding external links. Per guidelines, external links shouldn't be used in the body of an article. The reason I bring this up is your recent reversion of one of my edits to restriction enzyme (see diff), in which you restored an external link via the PDB template. Such external linking is absent throughout all of the relevant featured articles in biology (e.g. DNA repair, exosome complex, RNA interference), the recently promoted FA Rosetta@home and all of the protein-related good articles I looked through (e.g. Arp2/3 complex, Protein). Given that, shouldn't the PDB and PDB3 templates be deprecated? The PDB2 template seems like a viable alternative.
Also, given the MOS:IMAGES recommendation against forced sizing when images display well enough with the 180px default, shouldn't the 260px forced sizing you also restored in the 1qps image be removed as well? Cheers, Emw2012 ( talk) 22:10, 21 October 2008 (UTC)
Thank you for helping out with that. I just was doing Random Article Improvement. -- ₪ Amused Repose Converse! 22:29, 23 October 2008 (UTC)
(about the article KCNC1 Dear friend. You have "removed redundant URL from citation that contains a DOI, both point to the same page therefore no reason to include both, also DOIs are preferable since they are guaranteed not to change". However, I think that you did not take into account the all aspects of the issue. For example, article #7 (Rudy et al) also has a DOI. But this article has no open access, so providing the link with a url is senseless. But the article #4 (Gutman et al) has the open access. So, it is quite reasonable to provide this link also with url to underline the possibility for each user of Wikipedia to get the full text of the article using the link.-- Yuriy Kolodin ( talk) 13:49, 26 October 2008 (UTC)
Good edits. Carry on. -- Una Smith ( talk) 21:55, 27 October 2008 (UTC)
Darned nice of you. S B H arris 21:57, 28 October 2008 (UTC)
Your picture of the A2A receptor looks just great, I therefore wanted to ask you if you could the same for the TRPV1 channel. The PDB model is here: http://cbsm.utalca.cl/cecs/files/pdb/trpv1_pip2.zip, the reference is here: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1891241. Thanks Panoramix303 ( talk) 17:33, 31 October 2008 (UTC)
That article is unfortunately wrong. I know biocarta.com has the wrong transporter too. See Talk:Glutamate_aspartate_transporter. -- Ayacop ( talk) 16:43, 11 November 2008 (UTC)
Thanks for creating the LAG-3 article. You have put in a lot of references but none of them are in-line, which means I cannot tell what refers to what? -- 92.3.124.93 ( talk) 21:40, 14 November 2008 (UTC)
A tag has been placed on Image:L-tryptophan.png requesting that it be speedily deleted from Wikipedia. This has been done under section I8 of the criteria for speedy deletion, because it is available as a bit-for-bit identical copy on the Wikimedia Commons under the same name, or all references to the image on Wikipedia have been updated to point to the title used at Commons.
If you think that this notice was placed here in error, you may contest the deletion by adding {{
hangon}}
to the top of
the page that has been nominated for deletion (just below the existing speedy deletion or "db" tag), coupled with adding a note on [[ Talk:Image:L-tryptophan.png|the talk page]] explaining your position, but be aware that once tagged for speedy deletion, if the article meets the criterion it may be deleted without delay. Please do not remove the speedy deletion tag yourself, but don't hesitate to add information to the article that would would render it more in conformance with Wikipedia's policies and guidelines. Lastly, please note that if the article does get deleted, you can contact
one of these admins to request that a copy be emailed to you.
JaGa
talk
08:18, 16 November 2008 (UTC)
Thanks for noticing my image----it is for a specific protein but does fit in the same species as 7-dehydrocholesterol reductase which is why I added the image in the first place. I put it back on the page because this is for a biochem test and I need something up on that partcular page until she grades it. I will also be adding other comments and will remark on the fact that the image is realted but not exact. Thanks for your help. Whitek94 ( talk) 18:41, 18 November 2008 (UTC)
Hi Boghog2. Should these two pages be merged? GPR172A and GHB receptor or is there more than one GHB receptor? Also is GPR172A the same as GPR172? Meodipt ( talk) 11:44, 19 November 2008 (UTC)
Hi Boghog2. Do you know anything about this receptor? I can't find much but maybe it is one of those unidentified orphan GPCRs...there is some reasonable evidence for its existence here and a few selective ligands have been identified ( PMID 16719773 PMID 15246090) but then this paper ( PMID 15178356) says the apparent epsilon opioid receptor effects seem to be mediated through the classic opioid receptors instead so its a bit of a puzzle. Meodipt ( talk) 01:55, 1 December 2008 (UTC)
{{
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help)Hello Boghog and thanks for the editing and formating on the cugbp1 page. I have been wondering why the page is back to a minimal content page like the one originally created by the bot ?
This modification does not appear in the history.
OK, everything is back.yann —Preceding unsigned comment added by Yann.audic ( talk • contribs) 14:30, 4 December 2008 (UTC)
yann —Preceding unsigned comment added by Yann.audic ( talk • contribs) 14:26, 4 December 2008 (UTC)
Thanks for reviewing the changes I made. The citation you put in (Phospholipid scramblases: An overview) is basically what I used. I could go back an insert individual references. But I thought just having it there would be ok. What do you think? Artephius ( talk) 16:24, 5 December 2008 (UTC)
I'll get on that then. Artephius ( talk) 21:03, 5 December 2008 (UTC)
Hi Boghog, thank you for help. I am almost finished with the article, just remains som re-writing and citations about histology and determination in tissue extracts. Then I plan to continue with some other tumour marker.
By the way, on the discussion page, there is a remark about the article being an unimportnat stub. I do not know exactly the definition of a stub, but the article was not a stub when I started adding citations last week, and the enzyme is definitely not unimportant, as it is the deciding port of entry of several drugs and also importnat in clinical chemistry. Should this remark on the discussion page be modified? Lave ( talk) 07:25, 29 November 2008 (UTC)
Hejsan! Somebody is helping you to edit Tyrosine aminotransferase, but who is that person really and where do these images come from? I asked a question at commons:Commons:Village pump#Strange uploads. -- LA2 ( talk) 07:25, 11 December 2008 (UTC)
Though we rarely talk directly, I wanted to make sure you know how much I appreciate the wonderful work you do, and and how much I enjoy our silent collaboration. -- Arcadian ( talk) 01:27, 2 December 2008 (UTC)
I'd also like to thank you for the citation advice. I've got a lot to learn. Abe ( talk) 20:07, 14 December 2008 (UTC)
I hope that you have a happy Christmas and have a Happy New Year Bog. Try not to modulate those alpha subunits too much on New Years eve night!:=) LOL-- Literaturegeek | T@1k? 21:06, 22 December 2008 (UTC)
Hello, Boghog I noticed that you edited a link on the CLCNKB article back in July; the Homologene link is retired and I was trying to replace it with a link to Gene ( http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1188&ordinalpos=1&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum) but I don't know the code. Can you help? doctorwolfie ( talk) 11:18, 23 December 2008 (UTC)
Boghog: Gott Nytt År!! Allt gott under 2009! Lave ( talk) 12:28, 30 December 2008 (UTC)
Boghog2 thanx for welcoming me and the great advice too. i am part of a large group developing a grant application to the national inst of health to set up a web site to assist the community in learning about research on cleft lip and palate. we wanted to use the gene wikis as a common, easily accessible format to curate up to date information on genes especially relevant to cleft lip so a few of us will be trying to edit perhaps 20 or so gene entries. but we realize we are a specialized community so dont want to offend anyone. any advice or central resources we could access for this kind of work. thanx a lot we really love wikipedia and gene wikis especially. i will try to sign off the correct way i hope i get it right Jcmurray24 ( talk) 23:08, 30 December 2008 (UTC)