α-N-acetylglucosaminidase | |||||||
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Identifiers | |||||||
Symbol | NAGLU | ||||||
NCBI gene | 4669 | ||||||
HGNC | 7632 | ||||||
OMIM | 609701 | ||||||
RefSeq | NM_000263 | ||||||
UniProt | P54802 | ||||||
Other data | |||||||
EC number | 3.2.1.50 | ||||||
Locus | Chr. 17 q11-q21 | ||||||
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The enzyme α-N-acetylglucosaminidase ( EC 3.2.1.50, α-acetylglucosaminidase, N-acetyl-α-D-glucosaminidase, N-acetyl-α-glucosaminidase, α-D-2-acetamido-2-deoxyglucosidase) is a protein associated with Sanfilippo syndrome, with systematic name α-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase. [2] [3] [4] [5] It catalyses the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-α-D-glucosaminides, and also UDP-N-acetylglucosamine.
α-N-acetylglucosaminidase | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | NAGLU | ||||||
NCBI gene | 4669 | ||||||
HGNC | 7632 | ||||||
OMIM | 609701 | ||||||
RefSeq | NM_000263 | ||||||
UniProt | P54802 | ||||||
Other data | |||||||
EC number | 3.2.1.50 | ||||||
Locus | Chr. 17 q11-q21 | ||||||
|
The enzyme α-N-acetylglucosaminidase ( EC 3.2.1.50, α-acetylglucosaminidase, N-acetyl-α-D-glucosaminidase, N-acetyl-α-glucosaminidase, α-D-2-acetamido-2-deoxyglucosidase) is a protein associated with Sanfilippo syndrome, with systematic name α-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase. [2] [3] [4] [5] It catalyses the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-α-D-glucosaminides, and also UDP-N-acetylglucosamine.