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Formula | C28H32N6 |
Molar mass | 452.606 g·mol−1 |
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Tribendimidine is a broad-spectrum anthelmintic agent developed in China, at the National Institute of Parasitic Diseases in Shanghai. It is a derivative of amidantel. [1]
In clinical trials, it was highly effective in treating ankylostomiasis, ascariasis and enterobiasis. [2] It is also effective against clonorchiasis. [3] However, animal studies suggest it is ineffective in treating Schistosoma mansoni or Fasciola hepatica disease. [1] The drug has also performed well in trials against opisthorchiasis, curing about 70% of cases. [4]
Tribendimidine is manufactured by Shandong Xinhua Pharmaceutical Company Limited in Zibo, Shandong, China. It was approved by the China Food and Drug Administration in 2007.[ citation needed]
![]() | |
Clinical data | |
---|---|
ATC code |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C28H32N6 |
Molar mass | 452.606 g·mol−1 |
3D model ( JSmol) | |
| |
| |
![]() ![]() |
Tribendimidine is a broad-spectrum anthelmintic agent developed in China, at the National Institute of Parasitic Diseases in Shanghai. It is a derivative of amidantel. [1]
In clinical trials, it was highly effective in treating ankylostomiasis, ascariasis and enterobiasis. [2] It is also effective against clonorchiasis. [3] However, animal studies suggest it is ineffective in treating Schistosoma mansoni or Fasciola hepatica disease. [1] The drug has also performed well in trials against opisthorchiasis, curing about 70% of cases. [4]
Tribendimidine is manufactured by Shandong Xinhua Pharmaceutical Company Limited in Zibo, Shandong, China. It was approved by the China Food and Drug Administration in 2007.[ citation needed]