From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Tolloid-like protein 1 is a
protein that in humans is encoded by the TLL1
gene .
[5]
[6]
This gene encodes an
astacin -like zinc-dependent
metalloprotease and is a subfamily member of the
metzincin family. A similar protein in mice is required during heart development and specifically processes
procollagen C-propeptides and
chordin at similar cleavage sites.
[6]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000038295 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000053626 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Scott IC, Clark TG, Takahara K, Hoffman GG, Eddy RL, Haley LL, Shows TB, Greenspan DS (Oct 1999). "Assignment of TLL1 and TLL2, which encode human BMP-1/Tolloid-related metalloproteases, to chromosomes 4q32→q33 and 10q23→q24 and assignment of murine Tll2 to chromosome 19". Cytogenet Cell Genet . 86 (1): 64–65.
doi :
10.1159/000015412 .
PMID
10516436 .
S2CID
42081614 .
^
a
b
"Entrez Gene: TLL1 tolloid-like 1" .
Further reading
Takahara K, Brevard R, Hoffman GG, et al. (1997). "Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1". Genomics . 34 (2): 157–165.
doi :
10.1006/geno.1996.0260 .
PMID
8661043 .
Scott IC, Blitz IL, Pappano WN, et al. (1999).
"Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis" . Dev. Biol . 213 (2): 283–300.
doi :
10.1006/dbio.1999.9383 .
PMID
10479448 .
Scott IC, Imamura Y, Pappano WN, et al. (2000).
"Bone morphogenetic protein-1 processes probiglycan" . J. Biol. Chem . 275 (39): 30504–30511.
doi :
10.1074/jbc.M004846200 .
PMID
10896944 .
Uzel MI, Scott IC, Babakhanlou-Chase H, et al. (2001).
"Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures" . J. Biol. Chem . 276 (25): 22537–22543.
doi :
10.1074/jbc.M102352200 .
PMID
11313359 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–16903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–45.
doi :
10.1038/ng1285 .
PMID
14702039 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–2127.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Ge G, Zhang Y, Steiglitz BM, Greenspan DS (2006).
"Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains" . J. Biol. Chem . 281 (16): 10786–10798.
doi :
10.1074/jbc.M511111200 .
PMID
16507574 .