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Names | |
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Systematic IUPAC name
(11aR,13Ξ,14R,15S,15aR)-2,3,4,5,6,7,13-Heptahydroxy-9,17-dioxo-9,11,11a,13,14,15,15a,17-octahydrodibenzo[g,i]pyrano[3,2-b][1,5]dioxacycloundecine-14,15-diyl bis(3,4,5-trihydroxybenzoate) | |
Other names
1-desgalloyleugeniin
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Identifiers | |
3D model (
JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
KEGG | |
PubChem
CID
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CompTox Dashboard (
EPA)
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Properties | |
C34H26O22 | |
Molar mass | 786.56 g/mol |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Tellimagrandin I is an ellagitannin found in plants, such as Cornus canadensis, Eucalyptus globulus, Melaleuca styphelioides, Rosa rugosa, and walnut. It is composed of two galloyl and one hexahydroxydiphenyl groups bound to a glucose residue. It differs from Tellimagrandin II only by a hydroxyl group instead of a third galloyl group. It is also structurally similar to punigluconin and pedunculagin, two more ellagitannin monomers.
Tellimagrandin I has been shown to restore antioxidant enzyme activity in glucose- and oxalate-challenged rat cells [1] and affects Cu(II)- and Fe(II)-dependent DNA strand breaks. [2] [3] It has hepatoprotective effects on carbon tetrachloride- and d-galactosamine-stressed HepG2 cells [4] [5] and enhances peroxisomal fatty acid beta-oxidation in liver, increasing mRNA expression of PPAR alpha, ACOX1, and CPT1A. [6] It enhances gap junction communication and reduces tumor phenotype in HeLa cells [7] and inhibits invasion of HSV-1 [8] and HCV similar to eugeniin and casuarictin. [9]
![]() | |
Names | |
---|---|
Systematic IUPAC name
(11aR,13Ξ,14R,15S,15aR)-2,3,4,5,6,7,13-Heptahydroxy-9,17-dioxo-9,11,11a,13,14,15,15a,17-octahydrodibenzo[g,i]pyrano[3,2-b][1,5]dioxacycloundecine-14,15-diyl bis(3,4,5-trihydroxybenzoate) | |
Other names
1-desgalloyleugeniin
| |
Identifiers | |
3D model (
JSmol)
|
|
ChEBI | |
ChEMBL | |
ChemSpider | |
KEGG | |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C34H26O22 | |
Molar mass | 786.56 g/mol |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Tellimagrandin I is an ellagitannin found in plants, such as Cornus canadensis, Eucalyptus globulus, Melaleuca styphelioides, Rosa rugosa, and walnut. It is composed of two galloyl and one hexahydroxydiphenyl groups bound to a glucose residue. It differs from Tellimagrandin II only by a hydroxyl group instead of a third galloyl group. It is also structurally similar to punigluconin and pedunculagin, two more ellagitannin monomers.
Tellimagrandin I has been shown to restore antioxidant enzyme activity in glucose- and oxalate-challenged rat cells [1] and affects Cu(II)- and Fe(II)-dependent DNA strand breaks. [2] [3] It has hepatoprotective effects on carbon tetrachloride- and d-galactosamine-stressed HepG2 cells [4] [5] and enhances peroxisomal fatty acid beta-oxidation in liver, increasing mRNA expression of PPAR alpha, ACOX1, and CPT1A. [6] It enhances gap junction communication and reduces tumor phenotype in HeLa cells [7] and inhibits invasion of HSV-1 [8] and HCV similar to eugeniin and casuarictin. [9]