From Wikipedia, the free encyclopedia
(Redirected from Sulfadimezine)
Sulfamethazine
Clinical data
AHFS/ Drugs.com International Drug Names
ATC code
Identifiers
  • 4-amino-N-(4,6-dimethylpyrimidin-2-yl)
    benzene-1-sulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
NIAID ChemDB
CompTox Dashboard ( EPA)
ECHA InfoCard 100.000.315 Edit this at Wikidata
Chemical and physical data
FormulaC12H14N4O2S
Molar mass278.33 g·mol−1
3D model ( JSmol)
Melting point176 °C (349 °F)
  • O=S(=O)(Nc1nc(cc(n1)C)C)c2ccc(N)cc2
  • InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16) checkY
  • Key:ASWVTGNCAZCNNR-UHFFFAOYSA-N checkY
   (verify)

Sulfadimidine or sulfamethazine is a sulfonamide antibacterial.

There are non-standardized a abbreviations for it as "sulfadimidine" (abbreviated SDI [1] [2] and more commonly but less reliably b SDD [3] [4]) and as "sulfamethazine" (abbreviated SMT [5] [6] and more commonly but less reliably c SMZ [7] [8]). Other names include sulfadimerazine, sulfadimezine, and sulphadimethylpyrimidine.[ citation needed]

References

  1. ^ Romváry A, Simon F (1992). "Sulfonamide residues in eggs". Acta Veterinaria Hungarica. 40 (1–2): 99–106. PMID  1476095.
  2. ^ Reddy KS, Jain SK, Uppal RP (1988). "Pharmacokinetic studies of sulphonamides in poultry". Indian Journal of Animal Sciences.
  3. ^ Kamakura K, Hasegawa M, Koiguchi S, Miyata M, Okamoto K, Narita M, et al. (1993). "[Studies on the identification of sulfadimidine in pork by high performance liquid chromatography with photodiode array detector and gas chromatograph-mass spectrometry]". Eisei Shikenjo Hokoku. Bulletin of National Institute of Hygienic Sciences (111): 61–5. PMID  7920569.
  4. ^ Garg SK, Ghosh SS, Mathur VS (January 1986). "Comparative pharmacokinetic study of four different sulfonamides in combination with trimethoprim in human volunteers". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 24 (1): 23–5. PMID  3485584.
  5. ^ Peña MS, Salinas F, Mahedero MC, Aaron JJ (February 1994). "Solvent effect on the determination of sulfamethazine by room-temperature photochemically induced fluorescence". Talanta. 41 (2): 233–6. doi: 10.1016/0039-9140(94)80113-4. PMID  18965913.
  6. ^ Kaniou S, Pitarakis K, Barlagianni I, Poulios I (July 2005). "Photocatalytic oxidation of sulfamethazine". Chemosphere. 60 (3): 372–80. Bibcode: 2005Chmsp..60..372K. doi: 10.1016/j.chemosphere.2004.11.069. PMID  15924956.
  7. ^ Calvo R, Sarabia S, Carlos R, Du Souich P (Mar 1987). "Sulfamethazine absorption and disposition: effect of surgical procedures for gastroduodenal ulcers". Biopharmaceutics & Drug Disposition. 8 (2): 115–24. doi: 10.1002/bdd.2510080203. PMID  3593892.
  8. ^ De Liguoro M, Fioretto B, Poltronieri C, Gallina G (June 2009). "The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim". Chemosphere. 75 (11): 1519–24. Bibcode: 2009Chmsp..75.1519D. doi: 10.1016/j.chemosphere.2009.02.002. PMID  19269673.

Further reading

From Wikipedia, the free encyclopedia
(Redirected from Sulfadimezine)
Sulfamethazine
Clinical data
AHFS/ Drugs.com International Drug Names
ATC code
Identifiers
  • 4-amino-N-(4,6-dimethylpyrimidin-2-yl)
    benzene-1-sulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
NIAID ChemDB
CompTox Dashboard ( EPA)
ECHA InfoCard 100.000.315 Edit this at Wikidata
Chemical and physical data
FormulaC12H14N4O2S
Molar mass278.33 g·mol−1
3D model ( JSmol)
Melting point176 °C (349 °F)
  • O=S(=O)(Nc1nc(cc(n1)C)C)c2ccc(N)cc2
  • InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16) checkY
  • Key:ASWVTGNCAZCNNR-UHFFFAOYSA-N checkY
   (verify)

Sulfadimidine or sulfamethazine is a sulfonamide antibacterial.

There are non-standardized a abbreviations for it as "sulfadimidine" (abbreviated SDI [1] [2] and more commonly but less reliably b SDD [3] [4]) and as "sulfamethazine" (abbreviated SMT [5] [6] and more commonly but less reliably c SMZ [7] [8]). Other names include sulfadimerazine, sulfadimezine, and sulphadimethylpyrimidine.[ citation needed]

References

  1. ^ Romváry A, Simon F (1992). "Sulfonamide residues in eggs". Acta Veterinaria Hungarica. 40 (1–2): 99–106. PMID  1476095.
  2. ^ Reddy KS, Jain SK, Uppal RP (1988). "Pharmacokinetic studies of sulphonamides in poultry". Indian Journal of Animal Sciences.
  3. ^ Kamakura K, Hasegawa M, Koiguchi S, Miyata M, Okamoto K, Narita M, et al. (1993). "[Studies on the identification of sulfadimidine in pork by high performance liquid chromatography with photodiode array detector and gas chromatograph-mass spectrometry]". Eisei Shikenjo Hokoku. Bulletin of National Institute of Hygienic Sciences (111): 61–5. PMID  7920569.
  4. ^ Garg SK, Ghosh SS, Mathur VS (January 1986). "Comparative pharmacokinetic study of four different sulfonamides in combination with trimethoprim in human volunteers". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 24 (1): 23–5. PMID  3485584.
  5. ^ Peña MS, Salinas F, Mahedero MC, Aaron JJ (February 1994). "Solvent effect on the determination of sulfamethazine by room-temperature photochemically induced fluorescence". Talanta. 41 (2): 233–6. doi: 10.1016/0039-9140(94)80113-4. PMID  18965913.
  6. ^ Kaniou S, Pitarakis K, Barlagianni I, Poulios I (July 2005). "Photocatalytic oxidation of sulfamethazine". Chemosphere. 60 (3): 372–80. Bibcode: 2005Chmsp..60..372K. doi: 10.1016/j.chemosphere.2004.11.069. PMID  15924956.
  7. ^ Calvo R, Sarabia S, Carlos R, Du Souich P (Mar 1987). "Sulfamethazine absorption and disposition: effect of surgical procedures for gastroduodenal ulcers". Biopharmaceutics & Drug Disposition. 8 (2): 115–24. doi: 10.1002/bdd.2510080203. PMID  3593892.
  8. ^ De Liguoro M, Fioretto B, Poltronieri C, Gallina G (June 2009). "The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim". Chemosphere. 75 (11): 1519–24. Bibcode: 2009Chmsp..75.1519D. doi: 10.1016/j.chemosphere.2009.02.002. PMID  19269673.

Further reading


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