![]() | |
Names | |
---|---|
Preferred IUPAC name
Methyl bromoacetate | |
Other names
Bromoacetic acid methyl ester, Methyl α-bromoacetate
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.002.273 |
EC Number |
|
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
Properties | |
C3H5BrO2 | |
Molar mass | 152.975 g·mol−1 |
Density | 1.6±0.1 g/cm3 [1] |
Boiling point | 154 °C (309 °F; 427 K) |
Solubility | Soluble in water |
Hazards | |
GHS labelling: | |
![]() ![]() ![]() | |
Warning | |
H301, H311, H314, H335 | |
P233, P260, P261, P264, P270, P271, P280, P301, P302, P303, P304, P305, P310, P312, P321, P322, P330, P331, P338, P340, P351, P352, P353, P361, P363, P403, P405, P501 | |
Flash point | 63 °C (145 °F; 336 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Methyl 2-bromoacetate (methyl bromoactate) is a chemical compound with the molecular formula C3H5BrO2.
Methyl 2-bromoacetate is colorless or straw-colored liquid. The smell is sharp and penetrating. It is soluble in water and also has a higher density than water. [2] It is incompatible with acids, bases, oxidizing agents, and reducing agents. [3]
Methyl bromoacetate is an alkylating agent. It has been used to alkylate phenol and amino groups. [4] [5] Moreover, it can be used to make vitamins and pharmaceutical drugs. It is commonly used as a reagent in chemical modification of histidine. [2] In addition, methyl bromoacetate also use in synthesize of coumarins and cis-cyclopropane. It reacts with conjugated base and produce alkylated carbene complexes. [3]
Methyl bromoacetate can be toxic by ingestion and inhalation. It can also irritate the skin and eyes. [2]
![]() | |
Names | |
---|---|
Preferred IUPAC name
Methyl bromoacetate | |
Other names
Bromoacetic acid methyl ester, Methyl α-bromoacetate
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.002.273 |
EC Number |
|
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
Properties | |
C3H5BrO2 | |
Molar mass | 152.975 g·mol−1 |
Density | 1.6±0.1 g/cm3 [1] |
Boiling point | 154 °C (309 °F; 427 K) |
Solubility | Soluble in water |
Hazards | |
GHS labelling: | |
![]() ![]() ![]() | |
Warning | |
H301, H311, H314, H335 | |
P233, P260, P261, P264, P270, P271, P280, P301, P302, P303, P304, P305, P310, P312, P321, P322, P330, P331, P338, P340, P351, P352, P353, P361, P363, P403, P405, P501 | |
Flash point | 63 °C (145 °F; 336 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Methyl 2-bromoacetate (methyl bromoactate) is a chemical compound with the molecular formula C3H5BrO2.
Methyl 2-bromoacetate is colorless or straw-colored liquid. The smell is sharp and penetrating. It is soluble in water and also has a higher density than water. [2] It is incompatible with acids, bases, oxidizing agents, and reducing agents. [3]
Methyl bromoacetate is an alkylating agent. It has been used to alkylate phenol and amino groups. [4] [5] Moreover, it can be used to make vitamins and pharmaceutical drugs. It is commonly used as a reagent in chemical modification of histidine. [2] In addition, methyl bromoacetate also use in synthesize of coumarins and cis-cyclopropane. It reacts with conjugated base and produce alkylated carbene complexes. [3]
Methyl bromoacetate can be toxic by ingestion and inhalation. It can also irritate the skin and eyes. [2]