| Combination of | |
|---|---|
| Isoniazid | Anti-tuberculosis medication |
| Pyridoxine | Vitamin |
| Sulfamethoxazole | Antibiotic |
| Trimethoprim | Antibiotic |
| Clinical data | |
|
Routes of administration | By mouth [1] |
| ATC code | |
Isoniazid/pyridoxine/sulfamethoxazole/trimethoprim (INH/B6/CTX) is a fixed-dose combination medication for the prevention of opportunistic infections in HIV/AIDS. [1] It combines isoniazid, pyridoxine, sulfamethoxazole, and trimethoprim. [1] Specifically it is used to prevent tuberculosis, toxoplasmosis, pneumonia, malaria, and isosporiasis. [2] It is taken by mouth. [1]
Side effects may include trouble concentrating, numbness, vomiting, and rash. [2] Serious side effects may include liver problems. [2] Caution may be required in people with G6PD deficiency. [2] While it has not been well studied, use in pregnancy appears to be okay. [2]
It is on the World Health Organization's List of Essential Medicines. [1] While benefits include being able to take less pills, it is unclear if this version changes peoples adherence to treatment. [2] Other studies, however, have found fixed-dose combinations to be useful for this purpose. [2]
References
- ^ a b c d e World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl: 10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ a b c d e f g "Isoniazid + pyridoxine + sulfamethoxazole + trimethoprim (New formulation) -- Adults". World Health Organization (WHO). Archived from the original on July 30, 2015. Retrieved 13 December 2017.
 | This antiinfective drug article is a stub. You can help Wikipedia by expanding it. |
| Combination of | |
|---|---|
| Isoniazid | Anti-tuberculosis medication |
| Pyridoxine | Vitamin |
| Sulfamethoxazole | Antibiotic |
| Trimethoprim | Antibiotic |
| Clinical data | |
|
Routes of administration | By mouth [1] |
| ATC code | |
Isoniazid/pyridoxine/sulfamethoxazole/trimethoprim (INH/B6/CTX) is a fixed-dose combination medication for the prevention of opportunistic infections in HIV/AIDS. [1] It combines isoniazid, pyridoxine, sulfamethoxazole, and trimethoprim. [1] Specifically it is used to prevent tuberculosis, toxoplasmosis, pneumonia, malaria, and isosporiasis. [2] It is taken by mouth. [1]
Side effects may include trouble concentrating, numbness, vomiting, and rash. [2] Serious side effects may include liver problems. [2] Caution may be required in people with G6PD deficiency. [2] While it has not been well studied, use in pregnancy appears to be okay. [2]
It is on the World Health Organization's List of Essential Medicines. [1] While benefits include being able to take less pills, it is unclear if this version changes peoples adherence to treatment. [2] Other studies, however, have found fixed-dose combinations to be useful for this purpose. [2]
References
- ^ a b c d e World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl: 10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ a b c d e f g "Isoniazid + pyridoxine + sulfamethoxazole + trimethoprim (New formulation) -- Adults". World Health Organization (WHO). Archived from the original on July 30, 2015. Retrieved 13 December 2017.
|
| This antiinfective drug article is a stub. You can help Wikipedia by expanding it. |