Combination of | |
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Rifampicin | Rifamycin antibiotic |
Isoniazid | Anti-tuberculosis medication |
Pyrazinamide | Anti-tuberculosis medication |
Clinical data | |
Trade names | Rifater, Trifazid, others |
AHFS/ Drugs.com | FDA Professional Drug Information |
License data | |
Routes of administration | By mouth |
ATC code | |
Legal status | |
Legal status |
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Identifiers | |
CAS Number | |
PubChem CID | |
ChemSpider |
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KEGG | |
(verify) |
Rifampicin/isoniazid/pyrazinamide, also known as rifampin/isoniazid/pyrazinamide, and sold under the trade name Rifater, is a medication used to treat tuberculosis. [1] It is a fixed dose combination of rifampicin, isoniazid, and pyrazinamide. [1] It is used either by itself or along with other antituberculosis medication. [1] It is taken by mouth. [1]
Side effects are those of the underlying medications. [1] These may include poor coordination, loss of appetite, nausea, joint pain, feeling tired, and numbness. [2] Severe side effects include liver problems. [3] Use in those under the age of 15 may not be appropriate. [3] It is unclear if use in pregnancy is safe for the baby. [3]
Rifampicin/isoniazid/pyrazinamide was approved for medical use in the United States in 1994. [3] It is on the World Health Organization's List of Essential Medicines. [4]
The hope of a fixed-dose combination pill is to increase the likelihood that people will take all of three medications. [5] Also, if people forget to take one or two of their drugs, they might not then develop resistance to the remaining drugs.[ citation needed]
It is manufactured by Aventis.[ citation needed]
Combination of | |
---|---|
Rifampicin | Rifamycin antibiotic |
Isoniazid | Anti-tuberculosis medication |
Pyrazinamide | Anti-tuberculosis medication |
Clinical data | |
Trade names | Rifater, Trifazid, others |
AHFS/ Drugs.com | FDA Professional Drug Information |
License data | |
Routes of administration | By mouth |
ATC code | |
Legal status | |
Legal status |
|
Identifiers | |
CAS Number | |
PubChem CID | |
ChemSpider |
|
KEGG | |
(verify) |
Rifampicin/isoniazid/pyrazinamide, also known as rifampin/isoniazid/pyrazinamide, and sold under the trade name Rifater, is a medication used to treat tuberculosis. [1] It is a fixed dose combination of rifampicin, isoniazid, and pyrazinamide. [1] It is used either by itself or along with other antituberculosis medication. [1] It is taken by mouth. [1]
Side effects are those of the underlying medications. [1] These may include poor coordination, loss of appetite, nausea, joint pain, feeling tired, and numbness. [2] Severe side effects include liver problems. [3] Use in those under the age of 15 may not be appropriate. [3] It is unclear if use in pregnancy is safe for the baby. [3]
Rifampicin/isoniazid/pyrazinamide was approved for medical use in the United States in 1994. [3] It is on the World Health Organization's List of Essential Medicines. [4]
The hope of a fixed-dose combination pill is to increase the likelihood that people will take all of three medications. [5] Also, if people forget to take one or two of their drugs, they might not then develop resistance to the remaining drugs.[ citation needed]
It is manufactured by Aventis.[ citation needed]