From Wikipedia, the free encyclopedia
glucuronate-2-sulfatase
Identifiers
EC no. 3.1.6.18
CAS no. 98597-45-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a glucuronate-2-sulfatase ( EC 3.1.6.18) is an enzyme that catalyzes the chemical reaction of cleaving off the 2-sulfate groups of the 2-O-sulfo-D- glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase. This enzyme is also called glucurono-2-sulfatase. This enzyme participates in glycosaminoglycan degradation and glycan structures - degradation.

References

  • Shaklee PN, Glaser JH, Conrad HE (1985). "A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans". J. Biol. Chem. 260 (16): 9146–9. PMID  4019466.


From Wikipedia, the free encyclopedia
glucuronate-2-sulfatase
Identifiers
EC no. 3.1.6.18
CAS no. 98597-45-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a glucuronate-2-sulfatase ( EC 3.1.6.18) is an enzyme that catalyzes the chemical reaction of cleaving off the 2-sulfate groups of the 2-O-sulfo-D- glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase. This enzyme is also called glucurono-2-sulfatase. This enzyme participates in glycosaminoglycan degradation and glycan structures - degradation.

References

  • Shaklee PN, Glaser JH, Conrad HE (1985). "A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans". J. Biol. Chem. 260 (16): 9146–9. PMID  4019466.



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