DNA-formamidopyrimidine glycosylase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 3.2.2.23 | ||||||||
CAS no. | 78783-53-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
|
DNA-formamidopyrimidine glycosylase ( EC 3.2.2.23, Fapy-DNA glycosylase, deoxyribonucleate glycosidase, 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase, 2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase, formamidopyrimidine-DNA glycosylase, DNA-formamidopyrimidine glycosidase, Fpg protein) is an enzyme with systematic name DNA glycohydrolase (2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing). [1] FPG is a base excision repair enzyme which recognizes and removes a wide range of oxidized purines from correspondingly damaged DNA. [2] It was discovered by Zimbabwean scientist Christopher J. Chetsanga in 1975. [3]
This enzyme catalyses the following chemical reaction
This enzyme participates in processes leading to recovery from mutagenesis and/or cell death by alkylating agents.
{{
cite journal}}
: CS1 maint: numeric names: authors list (
link)
DNA-formamidopyrimidine glycosylase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 3.2.2.23 | ||||||||
CAS no. | 78783-53-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
|
DNA-formamidopyrimidine glycosylase ( EC 3.2.2.23, Fapy-DNA glycosylase, deoxyribonucleate glycosidase, 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase, 2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase, formamidopyrimidine-DNA glycosylase, DNA-formamidopyrimidine glycosidase, Fpg protein) is an enzyme with systematic name DNA glycohydrolase (2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing). [1] FPG is a base excision repair enzyme which recognizes and removes a wide range of oxidized purines from correspondingly damaged DNA. [2] It was discovered by Zimbabwean scientist Christopher J. Chetsanga in 1975. [3]
This enzyme catalyses the following chemical reaction
This enzyme participates in processes leading to recovery from mutagenesis and/or cell death by alkylating agents.
{{
cite journal}}
: CS1 maint: numeric names: authors list (
link)