Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a
protein that in humans is encoded by the EIF2S2gene.[5][6]
Function
Eukaryotic translation initiation factor 2 (
eIF2) functions in the early steps of
protein synthesis by forming a ternary complex with
GTP and initiator
tRNA and binding to a
40Sribosomal subunit. eIF2 is composed of three subunits,
alpha (α), beta (β, this article), and
gamma (γ), with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of
GDP for
GTP, which recycles the eIF2 complex for another round of initiation.[6]
Cai R, Carpick B, Chun RF, et al. (2000). "HIV-I TAT inhibits PKR activity by both RNA-dependent and RNA-independent mechanisms". Arch. Biochem. Biophys. 373 (2): 361–7.
doi:
10.1006/abbi.1999.1583.
PMID10620360.
Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a
protein that in humans is encoded by the EIF2S2gene.[5][6]
Function
Eukaryotic translation initiation factor 2 (
eIF2) functions in the early steps of
protein synthesis by forming a ternary complex with
GTP and initiator
tRNA and binding to a
40Sribosomal subunit. eIF2 is composed of three subunits,
alpha (α), beta (β, this article), and
gamma (γ), with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of
GDP for
GTP, which recycles the eIF2 complex for another round of initiation.[6]
Cai R, Carpick B, Chun RF, et al. (2000). "HIV-I TAT inhibits PKR activity by both RNA-dependent and RNA-independent mechanisms". Arch. Biochem. Biophys. 373 (2): 361–7.
doi:
10.1006/abbi.1999.1583.
PMID10620360.