![]() | This article may be too technical for most readers to understand.(October 2022) |
α-galactosidase | |||||||||
---|---|---|---|---|---|---|---|---|---|
![]() α-Galactosidase tetramer, Mortierella vinacea | |||||||||
Identifiers | |||||||||
EC no. | 3.2.1.22 | ||||||||
CAS no. | 9025-35-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
α-Galactosidase ( EC 3.2.1.22, α-GAL, α-GAL A; systematic name α-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyses the following reaction: [1]
It catalyzes many catabolic processes, including cleavage of glycoproteins, glycolipids, and polysaccharides.
The enzyme is encoded by the GLA gene. [2]
This enzyme is a homodimeric glycoprotein that hydrolyses the terminal α-galactosyl moieties from glycolipids and glycoproteins. It predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose.[ citation needed]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
![]() | This article may be too technical for most readers to understand.(October 2022) |
α-galactosidase | |||||||||
---|---|---|---|---|---|---|---|---|---|
![]() α-Galactosidase tetramer, Mortierella vinacea | |||||||||
Identifiers | |||||||||
EC no. | 3.2.1.22 | ||||||||
CAS no. | 9025-35-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
α-Galactosidase ( EC 3.2.1.22, α-GAL, α-GAL A; systematic name α-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyses the following reaction: [1]
It catalyzes many catabolic processes, including cleavage of glycoproteins, glycolipids, and polysaccharides.
The enzyme is encoded by the GLA gene. [2]
This enzyme is a homodimeric glycoprotein that hydrolyses the terminal α-galactosyl moieties from glycolipids and glycoproteins. It predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose.[ citation needed]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.