From Wikipedia, the free encyclopedia
Acetylajmaline esterase
Identifiers
EC no. 3.1.1.80
CAS no. 110183-46-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

The enzyme acetylajmaline esterase (EC 3.1.1.80, AAE, 2β(R)-17-O-acetylajmalan:acetylesterase, acetylajmalan esterase; systematic name 17-O-acetylajmaline O-acetylhydrolase) [1] [2] catalyses the following reactions:

(1) 17-O-acetylajmaline + H2O ajmaline + acetate
(2) 17-O-acetylnorajmaline + H2O norajmaline + acetate

This plant enzyme mediates the last stages in the biosynthesis of the indole alkaloid ajmaline.

References

  1. ^ Polz L, Schübel H, Stöckigt J (April 1987). "Characterization of 2β(R)-17-O-acetylajmalan: acetylesterase--a specific enzyme involved in the biosynthesis of the Rauwolfia alkaloid ajmaline". Zeitschrift für Naturforschung C. 42 (4): 333–42. PMID  2955586.
  2. ^ Ruppert M, Woll J, Giritch A, Genady E, Ma X, Stöckigt J (November 2005). "Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system". Planta. 222 (5): 888–98. doi: 10.1007/s00425-005-0031-0. PMID  16133216.
From Wikipedia, the free encyclopedia
Acetylajmaline esterase
Identifiers
EC no. 3.1.1.80
CAS no. 110183-46-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

The enzyme acetylajmaline esterase (EC 3.1.1.80, AAE, 2β(R)-17-O-acetylajmalan:acetylesterase, acetylajmalan esterase; systematic name 17-O-acetylajmaline O-acetylhydrolase) [1] [2] catalyses the following reactions:

(1) 17-O-acetylajmaline + H2O ajmaline + acetate
(2) 17-O-acetylnorajmaline + H2O norajmaline + acetate

This plant enzyme mediates the last stages in the biosynthesis of the indole alkaloid ajmaline.

References

  1. ^ Polz L, Schübel H, Stöckigt J (April 1987). "Characterization of 2β(R)-17-O-acetylajmalan: acetylesterase--a specific enzyme involved in the biosynthesis of the Rauwolfia alkaloid ajmaline". Zeitschrift für Naturforschung C. 42 (4): 333–42. PMID  2955586.
  2. ^ Ruppert M, Woll J, Giritch A, Genady E, Ma X, Stöckigt J (November 2005). "Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system". Planta. 222 (5): 888–98. doi: 10.1007/s00425-005-0031-0. PMID  16133216.

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