From Wikipedia, the free encyclopedia
(2,3-dihydroxybenzoyl)adenylate synthase
Identifiers
EC no. 2.7.7.58
CAS no. 122332-73-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a (2,3-dihydroxybenzoyl)adenylate synthase ( EC 2.7.7.58) is an enzyme that catalyzes the chemical reaction ATP + 2,3-dihydroxybenzoate diphosphate + (2,3-dihydroxybenzoyl)adenylate. [1]

Thus, the two substrates of this enzyme are ATP and 2,3-dihydroxybenzoate, whereas its two products are diphosphate and (2,3-dihydroxybenzoyl)adenylate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups ( nucleotidyltransferases). The systematic name of this enzyme class is ATP:2,3-dihydroxybenzoate adenylyltransferase. This enzyme is also called 2,3-dihydroxybenzoate-AMP ligase. This enzyme participates in biosynthesis of siderophore group nonribosomal.

References

  1. ^ Rusnak F, Faraci WS, Walsh CT (August 1989). "Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product". Biochemistry. 28 (17): 6827–6835. doi: 10.1021/bi00443a008. PMID  2531000.


From Wikipedia, the free encyclopedia
(2,3-dihydroxybenzoyl)adenylate synthase
Identifiers
EC no. 2.7.7.58
CAS no. 122332-73-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a (2,3-dihydroxybenzoyl)adenylate synthase ( EC 2.7.7.58) is an enzyme that catalyzes the chemical reaction ATP + 2,3-dihydroxybenzoate diphosphate + (2,3-dihydroxybenzoyl)adenylate. [1]

Thus, the two substrates of this enzyme are ATP and 2,3-dihydroxybenzoate, whereas its two products are diphosphate and (2,3-dihydroxybenzoyl)adenylate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups ( nucleotidyltransferases). The systematic name of this enzyme class is ATP:2,3-dihydroxybenzoate adenylyltransferase. This enzyme is also called 2,3-dihydroxybenzoate-AMP ligase. This enzyme participates in biosynthesis of siderophore group nonribosomal.

References

  1. ^ Rusnak F, Faraci WS, Walsh CT (August 1989). "Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product". Biochemistry. 28 (17): 6827–6835. doi: 10.1021/bi00443a008. PMID  2531000.



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