From Wikipedia, the free encyclopedia
Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase
Identifiers
EC no. 1.1.1.333
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
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NCBI proteins

Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase ( EC 1.1.1.333, decaprenylphospho-beta-D-ribofuranose 2'-epimerase, Rv3791, DprE2) is an enzyme with systematic name trans,octacis-decaprenylphospho-beta-D-arabinofuranose:NAD+ 2-oxidoreductase. [1] This enzyme catalyses the following chemical reaction

trans,octacis-decaprenylphospho-beta-D-arabinofuranose + NAD+ trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH + H+

The reaction is catalysed in the reverse direction.

References

  1. ^ Trefzer C, Škovierová H, Buroni S, Bobovská A, Nenci S, Molteni E, Pojer F, Pasca MR, Makarov V, Cole ST, Riccardi G, Mikušová K, Johnsson K (January 2012). "Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1". Journal of the American Chemical Society. 134 (2): 912–5. doi: 10.1021/ja211042r. PMID  22188377.

External links

From Wikipedia, the free encyclopedia
Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase
Identifiers
EC no. 1.1.1.333
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase ( EC 1.1.1.333, decaprenylphospho-beta-D-ribofuranose 2'-epimerase, Rv3791, DprE2) is an enzyme with systematic name trans,octacis-decaprenylphospho-beta-D-arabinofuranose:NAD+ 2-oxidoreductase. [1] This enzyme catalyses the following chemical reaction

trans,octacis-decaprenylphospho-beta-D-arabinofuranose + NAD+ trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH + H+

The reaction is catalysed in the reverse direction.

References

  1. ^ Trefzer C, Škovierová H, Buroni S, Bobovská A, Nenci S, Molteni E, Pojer F, Pasca MR, Makarov V, Cole ST, Riccardi G, Mikušová K, Johnsson K (January 2012). "Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1". Journal of the American Chemical Society. 134 (2): 912–5. doi: 10.1021/ja211042r. PMID  22188377.

External links


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