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![]() | Nocebo was a Natural sciences good articles nominee, but did not meet the good article criteria at the time. There may be suggestions below for improving the article. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake. | |||||||||
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Nocebo was featured in a WikiWorld cartoon. Click the image to the right for full size version. |
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This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available
on the course page. Student editor(s):
Cboughner.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 05:20, 17 January 2022 (UTC)
I am trying to update this page for a class and I wanted to know what anyone thinks of these as sources. [1]
and [2] both of these were retrieved from pubmed.gov. Cboughner ( talk) 03:59, 3 February 2018 (UTC)
References
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{{
cite journal}}
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Reverse Placebo Effect DOES NOT EQUAL nocebo. Nocebo (same root as Nociception) refers to negative or harmful effects that arise from the same reasons as the placebo effect (incidentally and contrary to this article, expectation is only one of the contributing factors). A good example of this is the study by Liccardi et al. (1) where subjects given placebo but told it was a medication to which they were allergic suffered a large number of negative symptoms. One can see how this is the same effect as placebo but in this case a negative or harmful (as opposed to therapeutic) response.
This contrasts Reverse Placebo in which case expectations opposite of what are expected occur in response to a placebo. In this case, taking a placebo analgesic (in which you expect and are conditioned to pain relief), you actually feel more pain (distinctly different from taking a drug that you expect and are conditioned to hyperalgesia). See paper by Bootzin et al. (2) for evidence of the different meaning of this term.
(1) Liccardi, G., Senna, G., Russo, M., Bonadonna, P., Crivellaro, M., Dama, A., ... & Passalacqua, G. (2004). Evaluation of the nocebo effect during oral challenge in patients with adverse drug reactions. Journal of Investigational Allergology and Clinical Immunology, 14(2), 104-7.
(2) Bootzin, R. R., & Bailey, E. T. (2005). Understanding placebo, nocebo, and iatrogenic treatment effects. Journal of clinical psychology, 61(7), 871-880)
There is clearly a vastly different meaning between these two terms. Reverse Placebo should NOT redirect here. -SRoy
RufioUniverse ( talk) 17:02, 30 April 2009 (UTC)
Ergoiamtoo, you suggested changing "It is self-evident that belief kills, etc." to "Some people believe that belief kills".
In my opinion, your version is very much better than mine; however, I have amended your "Some people believe that belief kills, etc." to read "Some people maintain that belief kills, etc."
I have done this simply because, in my opinion, the sentence reads a lot better because now it does not present two different meanings of the word "believe" in the same sentence. Also, I think the position of those who hold the view in question is far better represented by saying that "they maintain X" -- in the sense that they are externally asserting that X is the case -- rather than them just internally believing that X is the case, Hope that you agree with the amendment, as I feel that it makes things even more clear along the sensible lines that you have already suggested. cogtrue 10:44, 3 June 2006 (UTC)
Please can you remove the biblic quotation which is irrelevant and distracting to the topic. Please keep biblic quotations to pages relating to the bible or christianity.
I also found the quote strange and out of place. You could put part of your explanation on the page.
OK Lindsay658 21:26, 3 July 2006 (UTC)
The Good article nomination for Nocebo has failed, for the following reason:
One question comes to my mind. Is it a Nocebo effect when one takes medicine that someone believes won't help him, and while the body is cured the mind still suffers. This should probably be in the introduction as the introduction seems to only talk about placebos, however there's very good alternate items in the article (including self-willed deaths)
In addition self-willed vs. self-inflicted seems overexplained, with the bulk of the explination on self-inflicted. Shouldn't this be more about the different forms of self-willed. To my understanding self-willed is a unconcious act, self-inflicted is a concious act (walking in front of a bus with out noticing it vs. throwing yourself infront of a bus). There seems little use in explaining all three forms of self-inflicted acts (religious and heroic examples both fall firmly under suicide, though you could meantion "for heroic or religious means"). Kinglink 20:29, 6 September 2006 (UTC)
Unless I'm very much mistaken, the comic completely misrepresents what nocebo means. Needs to be removed. The fat guy dies bc. he does "not believe" in the power of a plcebo..... WTF???????? — Preceding unsigned comment added by 121.74.175.38 ( talk) 04:51, 4 May 2013 (UTC) _______
Random comment from the peanut gallery -- this article repeatedly uses quotes when they are not necessary. For example, there's no reason to refer to anything as a "classic" example ... saying a classic example is fine.
Steve
I removed "One known example is dying of fright after being bitten by a non- venomous snake", as a very similar story appears on Snopes, and is debunked there. I assume it's an urban legend. Ethan Mitchell ( talk) 01:07, 16 May 2008 (UTC)
Also this: "Because the original meaning of "nocebo" specifically referred to a subject's response to an inert drug, the term nocebo effect can really only refer to the consequences of the application of a "harm-producing" "nocebo drug" (however, the concept of a "harm-producing" "nocebo drug" is a much later concept than either that of a "nocebo response" or of a "nocebo reaction")." Makes no sense. Ethan Mitchell ( talk) 01:08, 16 May 2008 (UTC)
The intro sentence needs to be updated to provide a definition. - Ravedave ( talk) 20:40, 14 November 2008 (UTC)
Probably not an RS for anything, but still good. [1] Gråbergs Gråa Sång ( talk) 09:52, 24 December 2013 (UTC)
I've read the articles [1] and [2] linked to from this page and it seems to me that the TGN1412 was not a nocebo. The men who were given a low dose of the real drug became ill, while those who were given a placebo were OK. Why this case is even referenced at all? -- VadimIppolitov ( talk) 06:17, 7 April 2016 (UTC)
The last sentence reads: "Mental states such as beliefs and expectations can strongly influence the outcome of disease, the experience of pain, and even success of surgery.[3]" The attribution appears to be a popular science book. This is an extraordinary claim that I would think should require citation of (an) actual study/ies of high quality. If this sentence is unfounded, it is egregiously misleading, and should be removed as such.(?) Thanks.
![]() | Daily page views
|
![]() | Nocebo was a Natural sciences good articles nominee, but did not meet the good article criteria at the time. There may be suggestions below for improving the article. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake. | |||||||||
|
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Nocebo was featured in a WikiWorld cartoon. Click the image to the right for full size version. |
![]() |
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available
on the course page. Student editor(s):
Cboughner.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 05:20, 17 January 2022 (UTC)
I am trying to update this page for a class and I wanted to know what anyone thinks of these as sources. [1]
and [2] both of these were retrieved from pubmed.gov. Cboughner ( talk) 03:59, 3 February 2018 (UTC)
References
{{
cite journal}}
: Check |doi=
value (
help); External link in |doi=
(
help)
{{
cite journal}}
: |volume=
has extra text (
help); Check |doi=
value (
help); External link in |doi=
(
help)
Reverse Placebo Effect DOES NOT EQUAL nocebo. Nocebo (same root as Nociception) refers to negative or harmful effects that arise from the same reasons as the placebo effect (incidentally and contrary to this article, expectation is only one of the contributing factors). A good example of this is the study by Liccardi et al. (1) where subjects given placebo but told it was a medication to which they were allergic suffered a large number of negative symptoms. One can see how this is the same effect as placebo but in this case a negative or harmful (as opposed to therapeutic) response.
This contrasts Reverse Placebo in which case expectations opposite of what are expected occur in response to a placebo. In this case, taking a placebo analgesic (in which you expect and are conditioned to pain relief), you actually feel more pain (distinctly different from taking a drug that you expect and are conditioned to hyperalgesia). See paper by Bootzin et al. (2) for evidence of the different meaning of this term.
(1) Liccardi, G., Senna, G., Russo, M., Bonadonna, P., Crivellaro, M., Dama, A., ... & Passalacqua, G. (2004). Evaluation of the nocebo effect during oral challenge in patients with adverse drug reactions. Journal of Investigational Allergology and Clinical Immunology, 14(2), 104-7.
(2) Bootzin, R. R., & Bailey, E. T. (2005). Understanding placebo, nocebo, and iatrogenic treatment effects. Journal of clinical psychology, 61(7), 871-880)
There is clearly a vastly different meaning between these two terms. Reverse Placebo should NOT redirect here. -SRoy
RufioUniverse ( talk) 17:02, 30 April 2009 (UTC)
Ergoiamtoo, you suggested changing "It is self-evident that belief kills, etc." to "Some people believe that belief kills".
In my opinion, your version is very much better than mine; however, I have amended your "Some people believe that belief kills, etc." to read "Some people maintain that belief kills, etc."
I have done this simply because, in my opinion, the sentence reads a lot better because now it does not present two different meanings of the word "believe" in the same sentence. Also, I think the position of those who hold the view in question is far better represented by saying that "they maintain X" -- in the sense that they are externally asserting that X is the case -- rather than them just internally believing that X is the case, Hope that you agree with the amendment, as I feel that it makes things even more clear along the sensible lines that you have already suggested. cogtrue 10:44, 3 June 2006 (UTC)
Please can you remove the biblic quotation which is irrelevant and distracting to the topic. Please keep biblic quotations to pages relating to the bible or christianity.
I also found the quote strange and out of place. You could put part of your explanation on the page.
OK Lindsay658 21:26, 3 July 2006 (UTC)
The Good article nomination for Nocebo has failed, for the following reason:
One question comes to my mind. Is it a Nocebo effect when one takes medicine that someone believes won't help him, and while the body is cured the mind still suffers. This should probably be in the introduction as the introduction seems to only talk about placebos, however there's very good alternate items in the article (including self-willed deaths)
In addition self-willed vs. self-inflicted seems overexplained, with the bulk of the explination on self-inflicted. Shouldn't this be more about the different forms of self-willed. To my understanding self-willed is a unconcious act, self-inflicted is a concious act (walking in front of a bus with out noticing it vs. throwing yourself infront of a bus). There seems little use in explaining all three forms of self-inflicted acts (religious and heroic examples both fall firmly under suicide, though you could meantion "for heroic or religious means"). Kinglink 20:29, 6 September 2006 (UTC)
Unless I'm very much mistaken, the comic completely misrepresents what nocebo means. Needs to be removed. The fat guy dies bc. he does "not believe" in the power of a plcebo..... WTF???????? — Preceding unsigned comment added by 121.74.175.38 ( talk) 04:51, 4 May 2013 (UTC) _______
Random comment from the peanut gallery -- this article repeatedly uses quotes when they are not necessary. For example, there's no reason to refer to anything as a "classic" example ... saying a classic example is fine.
Steve
I removed "One known example is dying of fright after being bitten by a non- venomous snake", as a very similar story appears on Snopes, and is debunked there. I assume it's an urban legend. Ethan Mitchell ( talk) 01:07, 16 May 2008 (UTC)
Also this: "Because the original meaning of "nocebo" specifically referred to a subject's response to an inert drug, the term nocebo effect can really only refer to the consequences of the application of a "harm-producing" "nocebo drug" (however, the concept of a "harm-producing" "nocebo drug" is a much later concept than either that of a "nocebo response" or of a "nocebo reaction")." Makes no sense. Ethan Mitchell ( talk) 01:08, 16 May 2008 (UTC)
The intro sentence needs to be updated to provide a definition. - Ravedave ( talk) 20:40, 14 November 2008 (UTC)
Probably not an RS for anything, but still good. [1] Gråbergs Gråa Sång ( talk) 09:52, 24 December 2013 (UTC)
I've read the articles [1] and [2] linked to from this page and it seems to me that the TGN1412 was not a nocebo. The men who were given a low dose of the real drug became ill, while those who were given a placebo were OK. Why this case is even referenced at all? -- VadimIppolitov ( talk) 06:17, 7 April 2016 (UTC)
The last sentence reads: "Mental states such as beliefs and expectations can strongly influence the outcome of disease, the experience of pain, and even success of surgery.[3]" The attribution appears to be a popular science book. This is an extraordinary claim that I would think should require citation of (an) actual study/ies of high quality. If this sentence is unfounded, it is egregiously misleading, and should be removed as such.(?) Thanks.