This redirect does not require a rating on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||
|
|
|
Obviously this article is well-researched, but what are its sources? Are they at the listed "External Links"? It'd be nice to get cites and a proper reference list in there. DanB†DanD 19:58, 26 August 2006 (UTC)
I wrote much of this article (a good while back.) The sources of pretty much all of it is in the copylefted book I subsequently co-wrote (Medical Therapy and Health Maintenance for Transgender Men: A Guide For Health Care Providers) which was cited at the end of this article by someone after the fact. The original sources are in the book, and if I had the time I would try to clean this article up with regard to citations, but 1) I am not going to bet smacked around for original research and citing my own work and 2) don't have the time to do it with the original sources I used. :( Sorry. NickGorton 06:11, 3 November 2006 (UTC)
How about including the special case of HRT used in youths? HRT in youths precents most undesired secondary sexual charactoristics and better developed desired charactoristics. Also, it is common to block the onset of puberty "buying time" before starting HRT.
LexieM 01:53, 18 January 2006 (UTC)
Does the HRT change the size of the penis and the testicles or just the testicles?
Can Kiral please provide the source for his or her claims under Cardiovascular. Such as a study from PubMed or another reliable source, as the link given in the paragraph does not say anything about DHT, cortisol, etc. It also refers to 150mg tablets, however bicalutamide is very effective at a low dosage (even as low as 12mg) and has a long half-life. Most of the transwomen I've seen taking it use 12-50mg dosages, not 150mg. Also, I'm assuming what you are refering to is an Addisonian crisis, although those are typically caused by a withdrawal of corticosteroids. I've been searching on Google and PubMed but cannot find anything about a build up of DHT causing hypocortisolism upon withdrawal of using androgen receptor antagonists that would be reliable. I did, however, find one discussion board on an intersex website where one member says, "if your DHT levels get too high while taking an androgen receptor antagonist, you can have an adrenal crisis (hypocortisolism) when the antiandrogen wears off." They go on to say that they used Avodart to prevent such from happening. source
Since you do not have a talk page I cannot reach you directly, please consider becoming a member so others can contact you on your talk page. Thanks! -- WiccaIrish 19:41, 21 May 2006 (UTC)
I've rewritten this paragraph to include more references. I think the issue of adrenal problems is relevant, but if it's too controversial then we can take it out. I didn't include the bit about Avodart since these studies only tested bicalutamide with LHRH or orchiectomy. That doesn't mean Avodart isn't effective - it probably is - just that there aren't any formal studies of casodex + avodart. I'd also like to find a better citation for the stuff about fat solubility, since as you pointed out, the original pdf seems to have disappeared. --
Kiral 03:01, 24 May 2006 (UTC)
Question for the forum: While the chemical activity of common preperations of estrogen and anti-androgens are known; the effects observed effects of these hormone regimens is mostly studied via patient reporting. Should this verifiable lack of direct experimental evidence be more throrough noted within the wikipage?
Can the user who created: [5] section. Please provide sources for all claims therein. Note: While researchers have been able to isolate a "suspected" pheramone from male sweat, it is unclear if olefactor aroses or otherwise stimulates people who describe themselves as atracted to men.
Can the user who created:
[6]
Please provide sources for the section. In particular, is there research positively correlating metabolic processes to sex hormornes in natal women and/or in males who recieve HRT?
Note: I removed replaced the "tends" clause with "may" or "may be correlated."
Can the user who created:
Gland Development:Mammary Gland Development
Please provide sources.
Is it clear that the breast and nerve tissue development that natal males expierence with hormone thearpy -- is the same as what commonly occurs in natal women?
Note: Most research sources report that breast development in Natal Males who undergo HRT tends to take place over the 18-24 months. Reference the external link.
[7]
Also Note: Is there evidence showing that HRT patients who undergo breath augmentation tend to choose larger implants?
--
Sarah 00:23, 11 August 2006 (PST)
I've never heard this before: "the hips will rotate slightly forward due to changes in the tendons so hip discomfort is not uncommon." - is there any sourcing for this? -- Marumari 21:33, 14 August 2006 (UTC)
I was wondering that too... I hope this is true. Isn't there a hormone released in pregnant females that causes the pelvis to stretch and open more? What if transsexual women took this hormone? Would anything happen? Has this been experimented before?
Has there been any further information found about this? - 1958 6/24/16 — Preceding unsigned comment added by 107.77.192.224 ( talk) 23:58, 24 June 2016 (UTC)
If we supply a link to one branded formulation, we shouldn't refuse to supply the link to others.
Also, does anyone know what's available out of the US? I confess to being ignorant of that.
NickGorton 06:00, 3 November 2006 (UTC)
Since 2006 I've used Androgel, Androgel 1.62, Testim and Axiron. There are others on the market in the US but these are the most popular. Axiron being the newest on the market in the US. Since this topic is about Adrogel and Testim, I'll focus on those two products. I believe the regular Androgel has been replaced by the 1.62 version. The 1.62 gel has more testosterone per amount of gel. For example, applying 8 pumps of the regular Androgel is equal to 4 pumps of Androgel 1.62. Also, the regular Androgel had to be worn for 5 hours without exercise for maximum absorption. Androgel 1.62 has to be worn for at least 2 hours for maximum absorption.
Testim is a good product but it has a perfume added to it. If you know what Testim smells like, you know when someone is wearing it. If you don't like people knowing your business or that you're taking HRT, Testim might not be for you. I personally didn't like the smell and neither did my wife. When I spoke to my pharmacist, she said some guys like it because it has a musky smell. However, when I looked over her shoulder at the Testim on the shelf behind the counter, they had a bunch of it piling up. I'm sorry but it doesn't smell like drakkar noir, grey flannel or old spice. — Preceding unsigned comment added by Tommyt18 ( talk • contribs) 15:36, 5 March 2014 (UTC)
HRT does not usually cause facial hair growth to be impeded; or the voice to change. - Will whoever edits this page say if there is a way for that to be done?- —Preceding unsigned comment added by 72.64.63.200 ( talk • contribs) , posted in good faith
When testosterone levels are suppressed and/or androgens prevented from binding to androgen receptors, any further *new* hair growth would most likely be halted. Any follicles producing terminal hairs that currently exist would most likely have to be killed with electrolysis/laser (a bit more success with electro over laser), although this isn't always the case (those in their teens, for instance). Also, hair regrowth will likely be slower.
Any further drop to the voice would likely be halted as well (this applies to those still in puberty of course). -- WiccaIrish 03:13, 12 July 2007 (UTC)
A link on the SRS Male>Female page led me here I don't have the time to fix it. Could someone look into it for me? —Preceding unsigned comment added by 70.67.148.20 ( talk) 09:59, 22 June 2008 (UTC)
This redirect does not require a rating on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||
|
|
|
Obviously this article is well-researched, but what are its sources? Are they at the listed "External Links"? It'd be nice to get cites and a proper reference list in there. DanB†DanD 19:58, 26 August 2006 (UTC)
I wrote much of this article (a good while back.) The sources of pretty much all of it is in the copylefted book I subsequently co-wrote (Medical Therapy and Health Maintenance for Transgender Men: A Guide For Health Care Providers) which was cited at the end of this article by someone after the fact. The original sources are in the book, and if I had the time I would try to clean this article up with regard to citations, but 1) I am not going to bet smacked around for original research and citing my own work and 2) don't have the time to do it with the original sources I used. :( Sorry. NickGorton 06:11, 3 November 2006 (UTC)
How about including the special case of HRT used in youths? HRT in youths precents most undesired secondary sexual charactoristics and better developed desired charactoristics. Also, it is common to block the onset of puberty "buying time" before starting HRT.
LexieM 01:53, 18 January 2006 (UTC)
Does the HRT change the size of the penis and the testicles or just the testicles?
Can Kiral please provide the source for his or her claims under Cardiovascular. Such as a study from PubMed or another reliable source, as the link given in the paragraph does not say anything about DHT, cortisol, etc. It also refers to 150mg tablets, however bicalutamide is very effective at a low dosage (even as low as 12mg) and has a long half-life. Most of the transwomen I've seen taking it use 12-50mg dosages, not 150mg. Also, I'm assuming what you are refering to is an Addisonian crisis, although those are typically caused by a withdrawal of corticosteroids. I've been searching on Google and PubMed but cannot find anything about a build up of DHT causing hypocortisolism upon withdrawal of using androgen receptor antagonists that would be reliable. I did, however, find one discussion board on an intersex website where one member says, "if your DHT levels get too high while taking an androgen receptor antagonist, you can have an adrenal crisis (hypocortisolism) when the antiandrogen wears off." They go on to say that they used Avodart to prevent such from happening. source
Since you do not have a talk page I cannot reach you directly, please consider becoming a member so others can contact you on your talk page. Thanks! -- WiccaIrish 19:41, 21 May 2006 (UTC)
I've rewritten this paragraph to include more references. I think the issue of adrenal problems is relevant, but if it's too controversial then we can take it out. I didn't include the bit about Avodart since these studies only tested bicalutamide with LHRH or orchiectomy. That doesn't mean Avodart isn't effective - it probably is - just that there aren't any formal studies of casodex + avodart. I'd also like to find a better citation for the stuff about fat solubility, since as you pointed out, the original pdf seems to have disappeared. --
Kiral 03:01, 24 May 2006 (UTC)
Question for the forum: While the chemical activity of common preperations of estrogen and anti-androgens are known; the effects observed effects of these hormone regimens is mostly studied via patient reporting. Should this verifiable lack of direct experimental evidence be more throrough noted within the wikipage?
Can the user who created: [5] section. Please provide sources for all claims therein. Note: While researchers have been able to isolate a "suspected" pheramone from male sweat, it is unclear if olefactor aroses or otherwise stimulates people who describe themselves as atracted to men.
Can the user who created:
[6]
Please provide sources for the section. In particular, is there research positively correlating metabolic processes to sex hormornes in natal women and/or in males who recieve HRT?
Note: I removed replaced the "tends" clause with "may" or "may be correlated."
Can the user who created:
Gland Development:Mammary Gland Development
Please provide sources.
Is it clear that the breast and nerve tissue development that natal males expierence with hormone thearpy -- is the same as what commonly occurs in natal women?
Note: Most research sources report that breast development in Natal Males who undergo HRT tends to take place over the 18-24 months. Reference the external link.
[7]
Also Note: Is there evidence showing that HRT patients who undergo breath augmentation tend to choose larger implants?
--
Sarah 00:23, 11 August 2006 (PST)
I've never heard this before: "the hips will rotate slightly forward due to changes in the tendons so hip discomfort is not uncommon." - is there any sourcing for this? -- Marumari 21:33, 14 August 2006 (UTC)
I was wondering that too... I hope this is true. Isn't there a hormone released in pregnant females that causes the pelvis to stretch and open more? What if transsexual women took this hormone? Would anything happen? Has this been experimented before?
Has there been any further information found about this? - 1958 6/24/16 — Preceding unsigned comment added by 107.77.192.224 ( talk) 23:58, 24 June 2016 (UTC)
If we supply a link to one branded formulation, we shouldn't refuse to supply the link to others.
Also, does anyone know what's available out of the US? I confess to being ignorant of that.
NickGorton 06:00, 3 November 2006 (UTC)
Since 2006 I've used Androgel, Androgel 1.62, Testim and Axiron. There are others on the market in the US but these are the most popular. Axiron being the newest on the market in the US. Since this topic is about Adrogel and Testim, I'll focus on those two products. I believe the regular Androgel has been replaced by the 1.62 version. The 1.62 gel has more testosterone per amount of gel. For example, applying 8 pumps of the regular Androgel is equal to 4 pumps of Androgel 1.62. Also, the regular Androgel had to be worn for 5 hours without exercise for maximum absorption. Androgel 1.62 has to be worn for at least 2 hours for maximum absorption.
Testim is a good product but it has a perfume added to it. If you know what Testim smells like, you know when someone is wearing it. If you don't like people knowing your business or that you're taking HRT, Testim might not be for you. I personally didn't like the smell and neither did my wife. When I spoke to my pharmacist, she said some guys like it because it has a musky smell. However, when I looked over her shoulder at the Testim on the shelf behind the counter, they had a bunch of it piling up. I'm sorry but it doesn't smell like drakkar noir, grey flannel or old spice. — Preceding unsigned comment added by Tommyt18 ( talk • contribs) 15:36, 5 March 2014 (UTC)
HRT does not usually cause facial hair growth to be impeded; or the voice to change. - Will whoever edits this page say if there is a way for that to be done?- —Preceding unsigned comment added by 72.64.63.200 ( talk • contribs) , posted in good faith
When testosterone levels are suppressed and/or androgens prevented from binding to androgen receptors, any further *new* hair growth would most likely be halted. Any follicles producing terminal hairs that currently exist would most likely have to be killed with electrolysis/laser (a bit more success with electro over laser), although this isn't always the case (those in their teens, for instance). Also, hair regrowth will likely be slower.
Any further drop to the voice would likely be halted as well (this applies to those still in puberty of course). -- WiccaIrish 03:13, 12 July 2007 (UTC)
A link on the SRS Male>Female page led me here I don't have the time to fix it. Could someone look into it for me? —Preceding unsigned comment added by 70.67.148.20 ( talk) 09:59, 22 June 2008 (UTC)