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I think there's enough in both the signs & symptoms section and the diagnosis subsection that each could stand on their own. You might consider putting Diagnosis before Treatment per WP:MEDMOS. But I'll leave it to you to decide what flows better (and whether you need any of the info in the Dx section for understanding of pathophysiology). delldot ∇. 22:22, 2 October 2009 (UTC)
I've been doing a terminology paper on COPD, and I must conclude that characterizing DPB as "a type of chronic obstructive pulmonary disease", or even talking about "a type of" COPD seems to grossly misrepresent current understanding of COPD (while mildly excusable given this is about DPB, it is still unacceptable on a global level). The only papers actually referring to DPB as a COPD date back some 10 years, and their basis is the following (from Homma et al. 1983, PMID 6848335, 1st ref in the article):
This is NOT current terminology and I challenge anybody to find a recent work that treats COPD as a spectrum. At best there are discussions whether to include asthma in COPD, but bronchiolitis and its variants (i.e. bronchiolitis obliterans) are quite systematically discussed as a completely separate disease, quite understandably, since COPD has not been treated as a group of disease (besides, obviously, emphysema and bronchitis) since the mid-90s! Note that, for example, the abstract in ref 8 seems to explicitly discuss DPB and COPD as separate disease. Circéus ( talk) 02:41, 19 November 2009 (UTC)
Hmm. This can likely be resolved by a ce. In the article, though, I did not assert beyond PMID 9731015, 1998; nor PMID 9927368, 1999; both of which refer to DPB as a COPD. But, let me do a band-aid ce for the time being. heh.-- Robert/ Rcej ( talk) 09:02, 19 November 2009 (UTC)
I believe that the use of erythromycin as an anti-inflammatory macrolide is a little outdated. The frequency of treatment with erythromycin (four times a day) and its side-effect profile (mainly gastro-intestinal) have caused it to be replaced by azithromycin & clarithromycin. Axl ¤ [Talk] 20:08, 20 October 2011 (UTC)
Here is a draft that tries to make the essential information a bit more accessible. Experience has taught me that it is a bad idea to make such large changes directly, so I place it here for consideration.
Looie496 ( talk) 16:12, 1 November 2011 (UTC)
Perhaps put "small tubes that carry air into the lungs" in parentheses? Axl ¤ [Talk] 18:09, 1 November 2011 (UTC)
Chronic sinusitis is actually the most common feature. Axl ¤ [Talk] 18:11, 1 November 2011 (UTC)
"Impairment of the human leukocyte antigen (HLA) system results in a reduction of immune resistance to bacteria that are carried into the bronchioles by the airstream." Is that really true? Is HLA B54 an "impairment of the HLA system"? Axl ¤ [Talk] 18:24, 1 November 2011 (UTC)
DPB is not a purely genetic disease. HLA B54 certainly is a strong risk factor, but it is not the only one. Environmental factors also contribute. Axl ¤ [Talk] 18:35, 1 November 2011 (UTC)
Okay, I'll wait for Rcej to comment. Axl ¤ [Talk] 18:35, 1 November 2011 (UTC)
Best regards: Cliff (a/k/a "Uploadvirus") ( talk) 23:16, 3 December 2011 (UTC)
We should have an image in the lead and half of the CT one works well. Also the diagram of the respiratory system pertains to pathophysiology. Not sure why it is in the lead. Doc James ( talk · contribs · email) 09:23, 29 December 2011 (UTC)
I am reverting this edit. The source and basis of the information do not meet WP:MEDRS. Axl ¤ [Talk] 12:24, 23 November 2013 (UTC)
![]() | Diffuse panbronchiolitis is a featured article; it (or a previous version of it) has been identified as one of the best articles produced by the Wikipedia community. Even so, if you can update or improve it, please do so. | |||||||||||||||||||||
![]() | This article appeared on Wikipedia's Main Page as Today's featured article on January 15, 2012. | |||||||||||||||||||||
|
![]() | This article is rated FA-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||||||||||||||||||||||||||||||||||||||||
|
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Diffuse panbronchiolitis.
|
I think there's enough in both the signs & symptoms section and the diagnosis subsection that each could stand on their own. You might consider putting Diagnosis before Treatment per WP:MEDMOS. But I'll leave it to you to decide what flows better (and whether you need any of the info in the Dx section for understanding of pathophysiology). delldot ∇. 22:22, 2 October 2009 (UTC)
I've been doing a terminology paper on COPD, and I must conclude that characterizing DPB as "a type of chronic obstructive pulmonary disease", or even talking about "a type of" COPD seems to grossly misrepresent current understanding of COPD (while mildly excusable given this is about DPB, it is still unacceptable on a global level). The only papers actually referring to DPB as a COPD date back some 10 years, and their basis is the following (from Homma et al. 1983, PMID 6848335, 1st ref in the article):
This is NOT current terminology and I challenge anybody to find a recent work that treats COPD as a spectrum. At best there are discussions whether to include asthma in COPD, but bronchiolitis and its variants (i.e. bronchiolitis obliterans) are quite systematically discussed as a completely separate disease, quite understandably, since COPD has not been treated as a group of disease (besides, obviously, emphysema and bronchitis) since the mid-90s! Note that, for example, the abstract in ref 8 seems to explicitly discuss DPB and COPD as separate disease. Circéus ( talk) 02:41, 19 November 2009 (UTC)
Hmm. This can likely be resolved by a ce. In the article, though, I did not assert beyond PMID 9731015, 1998; nor PMID 9927368, 1999; both of which refer to DPB as a COPD. But, let me do a band-aid ce for the time being. heh.-- Robert/ Rcej ( talk) 09:02, 19 November 2009 (UTC)
I believe that the use of erythromycin as an anti-inflammatory macrolide is a little outdated. The frequency of treatment with erythromycin (four times a day) and its side-effect profile (mainly gastro-intestinal) have caused it to be replaced by azithromycin & clarithromycin. Axl ¤ [Talk] 20:08, 20 October 2011 (UTC)
Here is a draft that tries to make the essential information a bit more accessible. Experience has taught me that it is a bad idea to make such large changes directly, so I place it here for consideration.
Looie496 ( talk) 16:12, 1 November 2011 (UTC)
Perhaps put "small tubes that carry air into the lungs" in parentheses? Axl ¤ [Talk] 18:09, 1 November 2011 (UTC)
Chronic sinusitis is actually the most common feature. Axl ¤ [Talk] 18:11, 1 November 2011 (UTC)
"Impairment of the human leukocyte antigen (HLA) system results in a reduction of immune resistance to bacteria that are carried into the bronchioles by the airstream." Is that really true? Is HLA B54 an "impairment of the HLA system"? Axl ¤ [Talk] 18:24, 1 November 2011 (UTC)
DPB is not a purely genetic disease. HLA B54 certainly is a strong risk factor, but it is not the only one. Environmental factors also contribute. Axl ¤ [Talk] 18:35, 1 November 2011 (UTC)
Okay, I'll wait for Rcej to comment. Axl ¤ [Talk] 18:35, 1 November 2011 (UTC)
Best regards: Cliff (a/k/a "Uploadvirus") ( talk) 23:16, 3 December 2011 (UTC)
We should have an image in the lead and half of the CT one works well. Also the diagram of the respiratory system pertains to pathophysiology. Not sure why it is in the lead. Doc James ( talk · contribs · email) 09:23, 29 December 2011 (UTC)
I am reverting this edit. The source and basis of the information do not meet WP:MEDRS. Axl ¤ [Talk] 12:24, 23 November 2013 (UTC)