| sorbose reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.289 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a sorbose reductase ( EC 1.1.1.289) is an enzyme that catalyzes the chemical reaction
- D-glucitol + NADP+ L-sorbose + NADPH + H+
Thus, the two substrates of this enzyme are D-glucitol and NADP+, whereas its 3 products are L-sorbose, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glucitol:NADP+ oxidoreductase. This enzyme is also called Sou1p.
References
- Greenberg JR, Price NP, Oliver RP, Sherman F, Rustchenko E (2005). "Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization". Yeast. 22 (12): 957–69. doi: 10.1002/yea.1282. PMID 16134116.
- Rustchenko E (2005). "Erratum report: Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization". Yeast. 22 (14): 1171. doi: 10.1002/yea.1310.
- Sugisawa T, Hoshino T, Fujiwara A (1991). "Purification and properties of NADPH-linked L-sorbose reductase from Gluconobacter melanogenus N44-1". Agric. Biol. Chem. 55 (8): 2043–2049. doi: 10.1271/bbb1961.55.2043.
- Shinjoh M, Tazoe M, Hoshino T (2002). "NADPH-dependent L-sorbose reductase is responsible for L-sorbose assimilation in Gluconobacter suboxydans IFO 3291". J. Bacteriol. 184 (3): 861–3. doi: 10.1128/JB.184.3.861-863.2002. PMC 139518. PMID 11790761.
| sorbose reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.289 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a sorbose reductase ( EC 1.1.1.289) is an enzyme that catalyzes the chemical reaction
- D-glucitol + NADP+ L-sorbose + NADPH + H+
Thus, the two substrates of this enzyme are D-glucitol and NADP+, whereas its 3 products are L-sorbose, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glucitol:NADP+ oxidoreductase. This enzyme is also called Sou1p.
References
- Greenberg JR, Price NP, Oliver RP, Sherman F, Rustchenko E (2005). "Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization". Yeast. 22 (12): 957–69. doi: 10.1002/yea.1282. PMID 16134116.
- Rustchenko E (2005). "Erratum report: Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization". Yeast. 22 (14): 1171. doi: 10.1002/yea.1310.
- Sugisawa T, Hoshino T, Fujiwara A (1991). "Purification and properties of NADPH-linked L-sorbose reductase from Gluconobacter melanogenus N44-1". Agric. Biol. Chem. 55 (8): 2043–2049. doi: 10.1271/bbb1961.55.2043.
- Shinjoh M, Tazoe M, Hoshino T (2002). "NADPH-dependent L-sorbose reductase is responsible for L-sorbose assimilation in Gluconobacter suboxydans IFO 3291". J. Bacteriol. 184 (3): 861–3. doi: 10.1128/JB.184.3.861-863.2002. PMC 139518. PMID 11790761.